Research and Reviews in the Fastlane 101

This article reviews the evidence and concludes that the harms of prophylactic antibiotics likely outweighs the benefits and that withholding antibiotics may be very reasonable. Recommended by: Anand Swaminathan Pediatrics Cohen-Silver JH et al. Autism in the emergency department. Clin Pediatr 2014; 53(12): 1134-8. PMID: 25031320 Sometimes we need adjust our approach to a patient’s management in order to avoid exacerbating the problem. There are many clinical scenarios when this is true, but is especially important to consider when dealing with patients who have autism. Recommended by: Sean Fox Ultrasound and Imaging Silver SA et al. Risk prediction models for contrast induced nephropathy: systematic review. BMJ 2015. PMID: 26316642. This is a large systematic review exploring the ability of models to predict iodinated contrast induced nephropathy (CIN). Twelve prediction models were identified with varying degrees of validation. Most of these included similar risk factors as baseline renal dysfunction, diabetes, heart failure and hemodynamic compromise at the moment of the contrast administration. There is large heterogeneity in the ability to predict CIN, with some of the models with an excellent ability to do so, however these typically include the amount of volume used in the study, a variable only known post-hoc. Importantly, these predictive tools are mainly based on data from angiographic procedures instead of CT imaging. None of the models explored has bee...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Education Emergency Medicine Emergency Medicine Update General Surgery Infectious Disease Intensive Care Pediatrics R&R in the FASTLANE Radiology Urology critical care literature recommendations research and reviews Source Type: blogs