Modulation of cytokine gene expression by selected Lactobacillus isolates in the ileum, cecal tonsils, and spleen of Salmonella-challenged broilers.

Modulation of cytokine gene expression by selected Lactobacillus isolates in the ileum, cecal tonsils, and spleen of Salmonella-challenged broilers. Avian Pathol. 2015 Sep 22;:1-31 Authors: Hu JL, Yu H, Kulkarni RR, Sharif S, Cui SW, Xie MY, Nie SP, Gong J Abstract Probiotics have been used to control Salmonella colonization in the chicken intestine. Recently, we demonstrated that certain selected Lactobacillus isolates were able to reduce Salmonella infection in the chicken spleen and liver as well as down-regulated Salmonella pathogenicity island 1 (SPI-1) virulence gene expression in the chicken cecum. To further understand the mechanisms through which Lactobacillus protected chickens from Salmonella infection, the present study has investigated the Lactobacillus isolate(s)-induced host immune response of chickens to Salmonella infection. A thorough examination of cytokine gene expression in the ileum, cecal tonsils and spleen on days 1 and 3 post Salmonella infection showed a dynamic spatial and temporal response to Salmonella infection and Lactobacillus treatments. In most instances, it was evident that treatment of chickens with Lactobacillus isolates could significantly attenuate Salmonella-induced changes in the gene expression profile. These included the genes encoding pro-inflammatory cytokines [lipopolysaccharide-induced TNF factor (LITAF), interleukin (IL)-6, and IL-8], T helper (Th) 1 cytokines [IL-12 and interferon (IFN)-γ], and Th2 c...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research

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The objective of this study was to evaluate the effectiveness of pulsed light (PL) treatment, a novel antimicrobial (LAPEN) wash and combinations thereof in inactivating Salmonella on stem scars of cherry tomato. The treatment effects on background microbiota and sensory quality was also investigated while in storage for 21 days at 10 °C. Three serotypes of Salmonella enterica were chosen to prepare inoculum for the current investigation for their link with tomato and produce outbreaks. Stem scars of tomato were spot inoculated before being treated with PL (1–63 J/cm2), LAPEN sanitizer (2 min) or combinatio...
Source: Food Control - Category: Food Science Source Type: research
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Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
A Utah company is recalling two-pound frozen bags of Quest beef cat food sold nationwide over fears it may be contaminated with salmonella.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 14 November 2019Source: Carbohydrate PolymersAuthor(s): Ruzanna Ahmad Shapi’i, Siti Hajar Othman, Norhazirah Nordin, Roseliza Kadir Basha, Mohd Nazli NaimAbstractChitosan nanoparticles (CNP) were synthesized via ionic gelation and used for the preparation of starch-based nanocomposite films containing different concentration of CNP (0, 5, 10, 15, 20% w/w). Antimicrobial properties of starch/CNP films was evaluated via in vitro (disc diffusion analysis) and in vivo (microbial count in wrapped cherry tomatoes) study. It was found that inhibitory zone of the 15 and 20% of starch/CNP fi...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: Available online 14 November 2019Source: Microbial PathogenesisAuthor(s): Alaeldein M. Abudabos, Mashael R. Aljumaah, Manal M. Alkhlifi, Abdulaziz Alabdullatif, Gamal M. Suliman, Ali Ramzi AL SulaimanAbstractFree of Salmonella infection, a total of 600 broiler chicks (Ross 308) were randomly allotted to six dietary treatments (10 replicates) as follows: Negative control (only the basal diet); positive control (infected only); T1, infection + antibiotic (avilamycin); T2, infection + Bacillus subtilis and T3, Salmonella infection + Bacillus licheniformis. The results revealed t...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsWe found that EFVF is safe with regard to acute toxicity in rats as well as genotoxicity such as mutagenesis or clastogenesis under the present experimental conditions. These results might support the safety of EFVF as a potential therapeutic material for the traditional use or pharmaceutical development.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 14 November 2019Source: Food ChemistryAuthor(s): Selina Brighina, Cristina Restuccia, Elena Arena, Rosa Palmeri, Biagio FallicoAbstractThe antibacterial activities of the dicarbonyl compounds glyoxal (GO), methylglyoxal (MGO), 3-deoxyglucosone (3-DG) were assessed against Gram-positive and Gram-negative pathogenic and food spoilage bacteria, both in agarised and liquid assay system. The kinetics of dicarbonyls’ degradation at different antimicrobial assay conditions were studied, to determine the possible interference of the nutrient medium.In agarised assay system, GO and MGO exhib...
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Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Conditions:   Tonsillitis;   Postoperative Pain;   Cryotherapy Effect Intervention:   Dietary Supplement: 2 daily standard doses of vanilla-chocolate ice cream (cryotherapy) Sponsor:   University Hospital  " Sestre  Milosrdnice " Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: April 2017 Source:Veterinary Immunology and Immunopathology, Volume 186 Author(s): W.M. Quinteiro-Filho, A.S. Calefi, D.S.G. Cruz, T.P.A. Aloia, A. Zager, C.S. Astolfi-Ferreira, J.A. Piantino Ferreira, S. Sharif, J. Palermo-Neto A high ambient temperature is a highly relevant stressor in poultry production. Heat stress (HS) has been reported to reduce animal welfare, performance indices and increase Salmonella susceptibility. Salmonella spp. are major zoonotic pathogen that cause over 1 billion of human infections worldwide annually. Therefore, the current study was designed to analyze the effect of heat...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
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