Use of Tolvaptan in Outpatients

Tolvaptan, a vasopressin receptor antagonist, inhibits water reabsorption in the renal collecting ducts. Tolvaptan has been found to be highly effective in treating overhydration leading to heart failure. Subjects of the current study were 42 patients taking tolvaptan after hospital discharge. Subjects consisted of 10 patients with valvular heart disease, 9 with atrial fibrillation, 8 with dilated cardiomyopathy, 6 with overhydration, 4 with old myocardial infarction, 3 with hypertension, and 2 with some other condition (mean age: 76.3 years).
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Source Type: research