Deficiency in DNA repair pathways of peripheral blood mononuclear cells correlates with better clinical outcome of myeloma patients

DNA interstrand cross-linking (ICL) agents have an important impact in cancer treatment. However, the precise mechanisms contributing to differential response of patients to chemotherapy with these drugs are poorly understood.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2015 Category: Hematology Authors: M. Gkotzamanidou, E. Terpos, N.C. Munshi, M.A. Dimopoulos, V.L. Souliotis Source Type: research