Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2

Conclusions:
Elevated circulating IL-1β contributed to promote ER stress- induced myocytes apoptosis by affecting IRAK-2/CHOP pathway in DCM.

Source: Cardiovascular Diabetology - September 23, 2015 Category: Cardiology Authors: Zhongwei LiuNa ZhaoHuolan ZhuShunming ZhuShuo PanJing XuXuejun ZhangYong ZhangJunkui Wang Source Type: research