Officinalioside, a new lignan glucoside from Borago officinalis L.

Officinalioside, a new lignan glucoside from Borago officinalis L.
Nat Prod Res. 2015 Sep 18;:1-6
Authors: Samy MN, Hamed AN, Sugimoto S, Otsuka H, Kamel MS, Matsunami K
Abstract
A new lignan glucoside, officinalioside (1), was isolated from n-BuOH fraction of the aerial parts of Borago officinalis L., together with four known compounds: actinidioionoside (2), roseoside (3), crotalionoside C (4) and kaempferol 3-O-β-D-galactopyranoside (5). The structure of the new compound was established by means of spectroscopic and chemical analyses. Compounds 1 and 2 showed a moderate DPPH radical scavenging activity (IC50: 52.6 ± 1.70 and 41.3 ± 0.25 μM, respectively) comparable with that of the standard trolox (16.6 ± 2.2 μM) without any significant cytotoxicity towards human cell line A549 (IC50 > 100 μM).
PMID: 26382913 [PubMed - as supplied by publisher]

Source: Natural Product Research - September 18, 2015 Category: Biochemistry Authors: Samy MN, Hamed AN, Sugimoto S, Otsuka H, Kamel MS, Matsunami K Tags: Nat Prod Res Source Type: research