Applications of luminous bacteria enzymes in toxicology.

Applications of luminous bacteria enzymes in toxicology.
Comb Chem High Throughput Screen. 2015 Sep 16;
Authors: Kratasyuk VA, Esimbekova EN
Abstract
This review describes the principle and applications of bioluminescent enzymatic toxicity bioassays. This type of assays uses bacterial coupled enzyme systems: NADH:FMN-oxidoreductase and luciferase to replace living organisms in developing cost-competitive biosensors for environmental, medical and industrial applications. These biosensors instantly signal chemical and biological hazards and allow for detecting a great amount of toxic compounds with advantages associated with fast results, high sensitivity, simplicity, low cost and safety of the procedure.
PMID: 26377542 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - September 16, 2015 Category: Chemistry Authors: Kratasyuk VA, Esimbekova EN Tags: Comb Chem High Throughput Screen Source Type: research