Medical News Today: Beetroot juice benefits patients with heart failure
A new study that takes the experience of elite athletes who have a diet high in nitrates shows there are benefits for people with heart failure, too.
Conclusions:This retrospective study illustrates that there are patients for whom PSG gave a false-negative study. Patients who had negative PSG and positive HSAT are more likely to be older and have the diagnosis of hypertension. Sleep physicians may consider repeat testing with HSAT in patients with a negative PSG and clinical symptoms of OSA.Commentary:A commentary on this article appears in this issue on page 1839.Citation:Lipatov K, Hayek A, Ghamande S, Boethel C, Chen W, Jones S. Predictors of obstructive sleep apnea on home sleep apnea test after a negative attended polysomnography.J Clin Sleep Med. 2018;14(11):1889–1894.
ConclusionSevere acute malnutrition affects diastolic function in children which is reversible in most of these cases with rehabilitation. TDI is an easy and practical method for detection and follow-up of ventricular function in malnourished children.
A secondary analysis of CARMELINA trial data with linagliptin underlines that DDP-4 inhibitors are not linked to an increase in heart failure outcomes in patients with type 2 diabetes, say US researchers.Medscape Medical News
Hospitalized heart failure patients with prior bariatric surgery had lower mortality than those without prior surgery, even after matching for BMI.Medscape Medical News
Publication date: Available online 14 November 2018Source: Canadian Journal of CardiologyAuthor(s): Ludovic Appert, Aymeric Menet, Alexandre Altes, Pierre Vladimir Ennezat, Hélène Bardet-Bouchery, Camille Binda, Yves Guyomar, François Delelis, Anne-Laure Castel, Caroline Le Goffic, Raphaelle-Ashley Guerbaai, Pierre Graux, Christophe Tribouilloy, Sylvestre MaréchauxAbstractBackgroundWe hypothesized that preoperative electromechanical dyssynchrony amenable to cardiac resynchronization therapy (CRT) and QRS narrowing immediately after CRT are both correlated and have a cumulative impact on response...
Vapotherm yesterday priced an initial public offering, aiming to raise $56 million for its respiratory device. Exeter, N.H.-based Vapotherm developed the Precision Flow line of devices to provide high-velocity heated, humidified and oxygenated air to treat patients with conditions such as pneumonia, chronic obstructive pulmonary disease, asthma and heart failure. Some 1,200 of the devices have been sold in the U.S., mostly into hospital ICUs, the company said. Vapotherm said it plans to issue 4 million shares at $14 apiece, hitting the low end of its prior range. The offering also includes a 30-day underwrit...
ConclusionsOur early outcomes suggest that the CSS approach may reduce the incidence of right ventricular failure, bleeding, intubation time and ICU length of stay. Further studies are needed to fully elucidate the advantages of CSS LVAD implantation compared with median sternotomy.
(Mary Ann Liebert, Inc./Genetic Engineering News) Mice with heart failure that were treated with AAV8-based gene therapy to deliver the protein urocortin 3 (UCn3) had increased blood levels of UCn3 over a 5-week period and improved heart function.
ConclusionRespiratory muscle weakness was associated with an increased dead ‐space ventilation ratio aggravating ventilation–perfusion mismatch during exercise in patients with CHF.
Authors: Coluccia R, Raffa S, Ranieri D, Micaloni A, Valente S, Salerno G, Scrofani C, Testa M, Gallo G, Pagannone E, Torrisi MR, Volpe M, Rubattu S Abstract Oxidative stress is currently viewed as a key factor in the genesis and progression of Heart Failure (HF). The aim of this study was to characterize the mitochondrial changes linked to oxidative stress generation in circulating peripheral blood mononuclear cells isolated from chronic HF patients (HF_PBMCs) in order to highlight the involvement of mitochondrial dysfunction in the pathophysiology of HF. To assess the production of reactive oxygen species (ROS), ...