Incidence of CNS Injury for a Cohort of 111 Patients Treated with Proton Therapy for Medulloblastoma; LET and RBE Associations for Areas of Injury

This report investigates the incidence of CNS injury in a large cohort of medulloblastoma patients treated with craniospinal irradiation by proton radiotherapy. An overall incidence of 3.6% was found. No clear correlation was found between the sites of toxicity and elevated RBE due to higher linear energy transfer values.

Source: International Journal of Radiation Oncology * Biology * Physics - September 17, 2015 Category: Radiology Authors: Drosoula Giantsoudi, Roshan V. Sethi, Beow Y. Yeap, Bree R. Eaton, David H. Ebb, Paul A. Caruso, Otto Rapalino, Yen-Lin E. Chen, Judith Adams, Torunn I. Yock, Nancy J. Tarbell, Harald Paganetti, Shannon M. MacDonald Tags: Clinical Investigation Source Type: research