U.K. scientists ask to edit human embryo genes
(Reuters) — British scientists have applied for permission to edit the genes of human embryos in a series of experiments aimed at finding out more about the earliest stages of human development. Just months after Chinese scientists caused an international furor by saying they had genetically modified human embryos, Kathy Niakan, a stem cell scientist from London’s Francis Crick Institute, has asked the British government’s fertility regulator for a license to carry out similar experiments. In a statement about her application, which was made to the Human Fertilization & Embryology Authority, Niakan said she had no intention of genetically altering embryos for use in human reproduction, but aimed to deepen scientific understanding of how a healthy human embryo develops. “This knowledge may improve embryo development after in vitro fertilisation (IVF) and might provide better clinical treatments for infertility,” she said in a statement, adding that any donated embryos would be used for research purposes only. Scientists around the world are currently debating the potential future use of new genetic technology known as CRISPR-Cas9, which allows researchers to edit virtually any gene, including in human embryos. While the technology can enable scientists to find and change or replace genetic defects, critics say it also has the potential to create “designer babies” to order. A spokesman for the HFEA noted that British law bans ...
A high proportion of female veterans have been sexually assaulted, and victims of assault are more likely to be infertile, which can be a marker of overall health, research shows.Medscape Medical News
Treatment for cancer and other serious conditions involves toxic chemotherapy drugs, radiation and surgery that can cause infertility in women and men.
Conditions: Anovulatory Infertility; Abnormal Uterine Bleeding-Ovulatory Disorders; Polycystic Ovarian Syndrome; Hyperprolactinemia; Luteinized Unruptured Follicle Syndrome; Corpus Luteum Insufficiency; Ovarian Insufficiency Interventions: Drug: experimental group: Bushen Culuan Decoction and Clomiphene Citrate Tablets placebo; Drug: control group: Clomiphene Citrate Tablets and Bushen Culuan Decoction placebo Sponsors: Xiyuan Hospital of China Academy of Chinese Medical Sciences; Dongzhi...
Who gets access to fertility specialists in the U.S. says a lot about who we think "deserves" a family.
CONCLUSIONS: The results show that infertile couples suffer from infertility-related sexual and relationship concerns. An intervention study should be conducted to help these couples overcome such concerns. PMID: 30317866 [PubMed - as supplied by publisher]
Publication date: Available online 16 October 2018Source: Reproductive ToxicologyAuthor(s): Jisun Yun, Inha Lee, Young Bin Won, Jae Hoon Lee, Seok Kyo Seo, SiHyun Cho, Young Sik Choi, Byung Seok Lee, Bo Hyon YunAbstractThis retrospective study investigated and compared the incidence of congenital foetal anomalies after letrozole versus clomiphene citrate (CC) administration for infertility treatment. Data from 142 newborns were included: letrozole group, n = 83; CC group, n = 61. Congenital anomalies were found in 7.2% (6/83) patients in the letrozole group and 18.0% (11/61) patients in the CC g...
Research, published in BJU International, suggests that men who are infertile are more likely to have higher than normal blood sugar levels, potentially predisposing them to diabetes.MedicalXpress
(Wiley) An eight-week mindfulness-based program was effective for reducing stress and depressive symptoms while increasing general well-being in a study of infertile women.
(Wiley) In a study of 744 infertile men, prediabetes was found in 114 (15.4 percent) of participants.
ConclusionsPrematurity was associated with placental complications, diabetes and hypertension, subfertility and IVF groups, and in IVF pregnancies, donor oocytes and/or thawed embryos.