phoP , SPI1, SPI2 and aroA mutants of Salmonella Enteritidis induce a different immune response in chickens

In conclusion, SPI1 and phoP mutants induced protective immunity without inducing an inflammatory response and antibody production. Inoculation of chickens with the SPI2 and aroA mutants also led to protective immunity but was associated with inflammation and antibody production. The differences in interaction between the mutants and chicken host can be used for a more detailed understanding of the chicken immune system.
Source: Veterinary Research - Category: Veterinary Research Source Type: research