Transmural APD gradient synchronizes repolarization in the human left ventricular wall

Conclusion
The intrinsic transmural difference in APD compensates for the normal cardiac activation sequence, resulting in more homogeneous repolarization of the left ventricular wall. Our data suggest that the transmural repolarization differences do not fully explain the genesis of the T wave.

Source: Cardiovascular Research - September 16, 2015 Category: Cardiology Authors: Boukens, B. J., Sulkin, M. S., Gloschat, C. R., Ng, F. S., Vigmond, E. J., Efimov, I. R. Tags: Ion channels and arrhythmias Source Type: research