Rotavirus infection in children with diarrhoea at korle-bu teaching hospital in ghana.

ROTAVIRUS INFECTION IN CHILDREN WITH DIARRHOEA AT KORLE-BU TEACHING HOSPITAL IN GHANA. Jpn J Infect Dis. 2015 Sep 11; Authors: Damanka S, Adiku TK, Armah GE, Rodrigues O, Donkor ES, Nortey D, Asmah R Abstract Human rotavirus infection was studied over a 12-month period (January 2004 to January 2005) in children <5 years admitted with severe diarrhoea at the Korle-Bu Teaching Hospital in Accra, Ghana. Two hundred and six hospitalizations for diarrhoea were recorded during the period with 34% (70/206) being positive for rotavirus infection. Infection occurred throughout the year with peak rotavirus infection recorded during the month of March. Hospitalization associated with rotaviruses was most common in the 6-8 months age group and was associated with longer hospital stay (range: 1-46 days with mean length of stay of 4.8 days). Eight mortalities due to diarrhoea (3.9%) were recorded during the surveillance. The case fatality for rotavirus was 2.9% (2/70) and occurred in children <12 months old. Four rotavirus VP7 genotypes (G1, G2, G3 and G9) were detected. The predominant genotypes were G2(22.9%), G1(17.1%), G9(17.1%) and G3(12.9%). Mixed G types were also detected. The predominant VP4 genotypes (P types) were P[6] (40%), P[8] (21.4%), P[4] (4.3%) and P[9] (1.4%). The predominant rotavirus strains infecting children in Accra were G9P[6] (10%) and G1P[8] (8.6%). Strains with unusual genotypes such as G2P[8] and G(2/3)P[6] were ...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research