Lung 'filtering' technique can reduce transplant rejection

A new technique to recondition poorly functioning lungs and remove donor white blood cells has been used by researchers in an attempt to increase the number of lungs available for transplant, and at the same time reduce the risk of acute rejection.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Publication date: Available online 17 July 2018Source: Journal of Hospital InfectionAuthor(s): M. Monteagudo Vela, B. Zych, D. Garcia Saez, A. Simon
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
We describe a novel technique of punching a side branch hole through the wall of the stent to allow a left upper lobe stent to be placed through a stent directed into the left lower lobe in a Y configuration with a good clinic al outcome.Respiration
Source: Respiration - Category: Respiratory Medicine Source Type: research
Ronald Reagan UCLA Medical Center led the nation in the number of solid organ transplants performed in 2017, with 641 procedures that included kidney, pancreas, lung, heart and intestine transplants, according to statistics from the Organ Procurement and Transplantation Network.UCLA recorded 363 kidney transplants in 2017, making it the year ’s top kidney transplant center.Other medical centers with a high number of solid organ transplants in 2017 were UC San Francisco; Jackson Memorial Hospital in Miami, Barnes-Jewish Hospital in St. Louis, Missouri; and the University of Wisconsin ’s University Hospital in Ma...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
We present a case of an adult male who underwent bilateral lung transplantation, with the native lung pathology showing diffuse, severe dendriform ossification of the bilateral upper and lower lung lobes. The gross and histologic findings along with the radiographic imaging are reviewed herein. Overall, primary ossification of the lung leading to lung transplant is a rare condition that pulmonologists caring for patients with interstitial lung disease should be aware of as a possible cause of the patient ’s symptoms and lung dysfunction.
Source: Virchows Archiv - Category: Pathology Source Type: research
Condition:   Transplant Failure Intervention:   Other: BLOOD SAMPLE ANALYSIS Sponsors:   Assistance Publique Hopitaux De Marseille;   Vaincre la Mucoviscidose Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Emerging clinical evidence has suggested that short-term mechanical augmentation of cardiac output (CO) may not consistently improve mortality in patients with cardiogenic shock (CS), despite improvements in hemodynamics. Such failures could reflect the underlying complexity of the mechanisms that contribute to malperfusion and organ dysfunction in CS. Distinct molecular and physiologic shock endophenotypes likely exist among patients with CS, with hemodynamic aberrations as the inciting insult, but not necessarily the primary drivers of clinical outcomes.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Perspective Source Type: research
We presently forget 98% of everything we experience. That will go away in favor of perfect, controllable, configurable memory. Skills and knowledge will become commodities that can be purchased and installed. We will be able to feel exactly as we wish to feel at any given time. How we perceive the world will be mutable and subject to choice. How we think, the very fundamental basis of the mind, will also be mutable and subject to choice. We will merge with our machines, as Kurzweil puts it. The boundary between mind and computing device, between the individual and his or her tools, will blur. Over the course of the ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Eighty five percent of congenital heart disease patients currently survive to adulthood due primarily to advancements in surgical treatments1. For these survivors with Adult Congenital Heart Disease (ACHD), heart failure (HF) remains the leading cause of death2. Thus, the number of ACHD patients requiring heart transplantation (HT) continues to grow, and with this growth has come improvements in outcomes. In 2009, Lamour et al. demonstrated a 1-year survival of 83% for non-Fontan congenital HT and 71% for patients with Fontan palliation3.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
Treatment decisions in dilated cardiomyopathy (DCM) patients with severe heart failure (HF) and short clinical history are challenging because of the difficulty of determining HF stage or prognosis in the acute HF phase. We hypothesized that persistent decreased systemic or increased pulmonary arterial pressure, including in the subclinical phase, may affect the main pulmonary artery diameter (PAD), ascending aortic diameter (AoD), and their ratio (PAD/AoD). The aims of this study were to assess AoD, PAD, and PAD/AoD by non-contrast computed tomography (CT) scans in DCM patients in the acute phase of HF and to examine the ...
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
Nowadays, a number of heart failure (HF) patients live with left ventricular assist devices (LVADs) implanted either as a destination therapy or as a bridge to heart transplant or to heart transplant candidacy.1,2 In all these cases, LVAD usually remains for a prolonged time after post-surgical stabilization, during which patients ’ daily quality of life must be improved as much as possible. LVADs are usually set at a fixed number of revolutions per minute (rpm), so that LVAD output changes during daily activities are only preload- and afterload-dependent, with limited variability.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
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