Secretion rates of human nasal submucosal glands from patients with chronic rhinosinusitis or cystic fibrosis.

CONCLUSION: The only significant difference in this small study was decreased forskolin-stimulated secretion in subjects with CF relative to the other subjects. However, there was a trend toward reduced carbachol-stimulated secretion rates in subjects with CRS and with and without CF relative to controls. Additional studies are needed to determine if nasal submucosal gland hyposecretion occurs in CRS either as a contributor to or as a consequence of CRS pathogenesis. PMID: 26358343 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/26358343?dopt=Abstract

Source: American Journal of Rhinology and Allergy - September 1, 2015 Category: ENT & OMF Authors: Jeong JH, Hwang PH, Cho DY, Joo NS, Wine JJ Tags: Am J Rhinol Allergy Source Type: research