Osteomyelitis of the Mandible in an Adolescent

Source: Journal of Dentistry for Children - Category: Dentistry Authors: Source Type: research

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Osteomyelitis occurs when microorganisms gain access to bone through contiguous dissemination, hematogenous seeding, or direct inoculation, leading to inflammatory changes and bone necrosis, hallmarks of the disease [1,2]. Compared to acute, chronic osteomyelitis is characterized by sinus tract and sequestrum development with vague symptoms. Although it was among the first infectious processes recorded, chronic osteomyelitis remains one of the most difficult to diagnose relying on a combination of clinical suspicion, laboratory, radiographic, and microbiologic findings.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research
DISCUSSION: Forty-one percent of children in this multicenter cohort underwent at least one repeat surgical procedure after the index arthrotomy for management of presumed SAH. Risk factors for return to the operating room include elevated initial erythrocyte sedimentation rate and C-reactive protein, infection with MRSA, and presence of osteomyelitis. LEVEL OF EVIDENCE: Level 3, case-cohort series. Type of evidence, therapeutic. PMID: 30520802 [PubMed - as supplied by publisher]
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
Authors: Khalil JG, Gandhi SD, Park DK, Fischgrund JS Abstract Cutibacterium acnes, long thought to be skin flora of pathological insignificance, has seen a surge in interest for its role in spine pathology. C acnes has been identified as a pathogen in native spine infection and osteomyelitis, which has implications in the management compared with more commonly recognized pathogens. In addition, It has also been recognized as a pathogen in postoperative and implant-associated infections. Some evidence exists pointing to C acnes as an unrecognized source of otherwise aseptic pseudarthrosis. Recently, it is hypothesi...
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
Septic arthritis is a dangerous medical condition associated with significant morbidity and mortality. However, the differential diagnosis can be broad with conditions that mimic this disease and require different evaluation and treatment. This narrative review presents the emergency medicine evaluation and management, as well as important medical conditions that may mimic this disease. Septic arthritis commonly presents with monoarticular joint pain with erythema, warmth, swelling, and pain on palpation and movement. Fever is present in many patients, though most are low grade. Blood testing and imaging may assist with th...
Source: Western Journal of Emergency Medicine - Category: Emergency Medicine Source Type: research
We report a case of Scedosporium apiospermum (S. apiospermum) CIFR with an atypical clinical and radiological presentation.Case reportA 72-year-old immunocompetent man presented with chronic headache, neck pain and bilateral limitation of lateral gaze. Imaging revealed an isolated left sphenoidal lesion with marked bone changes and an extradural abscess over the clivus. Large endoscopic sphenoidotomy with type II rhinopharyngectomy was performed and the diagnosis of S. apiospermum CIFR was based on histological examination and fungal culture. The patient refused all medical treatment and did not present any ...
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
AbstractPelvic osteomyelitis may occur in ametaphyseal equivalent, defined as a portion of flat or irregular bone that is adjacent to cartilage. The pelvic bone is known to have several metaphyseal equivalents and of these, the sacroiliac joint is the most frequent site of involvement. However, a sacral neurocentral synchondrosis has not been recognized as a metaphyseal equivalent, and there have been no previous reports describing this as the site of origin of sacral osteomyelitis. We here report two cases of sacral osteomyelitis originating in a neurocentral synchondrosis, another metaphyseal equivalent. We, as pediatric...
Source: Skeletal Radiology - Category: Radiology Source Type: research
C. H. Heath et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Publication date: Available online 30 November 2018Source: The Veterinary JournalAuthor(s): Daniel EladAbstractDisseminated canine mold infections are reviewed. Case inclusion criteria were dogs as hosts, two or more non-adjacent organs affected and identification of the etiological agent at least to the genus level. Of the 157 cases identified, 59.3% were caused by Aspergillus spp. of which 36.3% belonged to the section Terrei. German Shepherd breed dogs constituted 67.8% of the cases, 89.7% of which were caused by fungi of the section Terrei. Female dogs constituted 72.7% of the cases. The average age was 4.3 years (rang...
Source: The Veterinary Journal - Category: Veterinary Research Source Type: research
This study provides novel insights to understand the effect of different antimicrobial therapies in vivo, and a promising comprehensive methodology to evaluate the health state of the animals was developed. We expect that the implementation of such methodology could improve the criteria to select a proper antimicrobial therapy.Graphical abstract
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Future Microbiology, Ahead of Print.
Source: Future Microbiology - Category: Microbiology Authors: Source Type: research
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