Arieti and Bowlby: convergence and direct influence.
Arieti and Bowlby: convergence and direct influence. Am J Psychoanal. 2015 Sep;75(3):320-32 Authors: Bacciagaluppi M Abstract Arieti was a great specialist of schizophrenia and Bowlby was the initiator of attachment theory. Working independently on the two sides of the Atlantic, they converged on a range of topics, such as evolutionary theory, mourning, trauma, violence, and therapy as art and science. Later, Bowlby exerted a direct influence on Arieti, which Arieti acknowledged in his Love Can Be Found. Finally, the two authors cooperated in the second edition of the American Handbook of Psychiatry. PMID: 26356777 [PubMed - in process]
Authors: Lavallé L, Aleman A PMID: 31101378 [PubMed - as supplied by publisher]
A compound present in broccoli sprouts could change a chemical imbalance that characterizes the brains of people with schizophrenia.
We examined alterations in markers of muscarinic neurotransmission in the pre-frontal cortex (PFC) and hippocampus (HPC) following CBD treatment. Pregnant Sprague-Dawley rats (n = 16) were administered poly I:C (4 mg/kg) or saline. Adult offspring were treated (3-weeks) with CBD (10 mg/kg) or vehicle. Receptor autoradiography (using [3H]pirenzepine) was used to examine changes in muscarinic M1/M4 receptor (M1/M4R) binding density. Levels of choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) protein expression were examined using Western blot. M1/M4R binding density was downregulated in the PFC and CA1...
CONCLUSIONS: MMP-9 rs3918242 polymorphism may not be associated with schizophrenia. Given a crucial role of MMP-9 molecule on the pathogenesis of schizophrenia, this result should be verified by more studies with scientifically rigorous design and large population. PMID: 31094241 [PubMed - as supplied by publisher]
Conclusion: Previous studies and ours suggest an effect of truncating mutations restricted to severe autism-spectrum disorder phenotypes that are associated with intellectual disability. We provide evidence for pleiotropic effects of common and rare variants in the LRP1 gene across psychiatric phenotypes. PMID: 31094488 [PubMed - as supplied by publisher]
Neuropsychopharmacology, Published online: 18 May 2019; doi:10.1038/s41386-019-0417-5Neural and behavioral effects of oxytocin administration during theory of mind in schizophrenia and controls: a randomized control trial
Publication date: Available online 17 May 2019Source: Respiratory Medicine Case ReportsAuthor(s): Yazan Zayed, Danielle Osterholzer, Emily Armstrong, Qazi Azher, Ghassan BachuwaAbstractA 57-year-old male with schizophrenia and a 37 pack-year smoking history presented with cough productive of purulent sputum associated with hemoptysis and worsening shortness of breath. Computed tomography (CT) scan revealed multiple masses in the right upper and lower lobes with a small distal tracheal mass and significant mediastinal lymphadenopathy. CT guided biopsy of the largest lung mass in the right lower lobe confirmed a diagnosis of...
DiscussionBaseline P3a ERP, and PANSS general score were significant and independent predictors of later MCAS functioning at 12-month. Overall, individuals with worse functioning and greater symptomology produced smaller amplitudes. Our results highlight the heterogeneity within the FEP population. Correlation patterns among ERPs are similar between patients and controls. P3a and P3b amplitudes appear to link with higher-order cognitive and psychosocial functioning.
CONCLUSION: Risperidone loaded chitosan nanoparticles were effective against schizophrenia via intranasal route. PMID: 31094571 [PubMed - as supplied by publisher]
Publication date: Available online 16 May 2019Source: Journal of Psychiatric ResearchAuthor(s): Emma L. Hawkins, Roxanne D. Hawkins, Martin Dennis, Joanne M. Williams, Stephen M. LawrieAbstractAnimal-assisted therapy (AAT) is increasingly researched as a potential treatment for physical and mental illness, including schizophrenia. The aim of the current paper is to systematically review randomised controlled trials (RCTs) to assess the effectiveness of AAT for schizophrenia and related disorders. We searched PubMed, PsycINFO, CINAHL, EMBASE, The Cochrane Library, CAB Abstracts, and Web of Science for RCTs of AAT for schizo...