Innervation imaging in arrhythmia and arrhythmogenic disease

Abstract Cardiac innervation imaging with 123I-meta-iodobenzylguanidine scintigraphy or 11C-meta-hydroxyephedrine positron emission tomography visualizes and quantifies the activity of the sympathetic nervous system. No other imaging modality is able to stratify this potentially important trigger for various cardiac diseases. Recent literature has focussed mostly on its prognostic ability in heart failure patients, but its use is not limited to heart failure alone. In this review, the literature regarding cardiac innervation imaging in arrhythmia and arrhythmogenic syndromes is discussed, which shows potential for further study into the prognostic and diagnostic value of innervation imaging for atrial fibrillation and arrhythmogenic right ventricular cardiomyopathy especially.
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research