Risk score decides who gets invasive colorectal screening

A new risk assessment system could decide who needs to be screened for colorectal...Read more on AuntMinnie.comRelated Reading: Study questions evidence that screening reduces mortality Italian men shun flexible sigmoidoscopy for CTC No cost difference between CTC, colonoscopy in elderly CDC: Cancer screening compliance is lagging Optical colonoscopy misses polyps detected on CTC
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Colorectal cancer (CRC) screening is capable of reducing CRC-related morbidity and mortality. Colonoscopy is the reference standard to detect CRC, also providing the opportunity to detect and resect its precursor lesions; colorectal polyps. Therefore, colonoscopy is either used as a primary screening tool or as a subsequent procedure after a positive triage test in screening programs based on non-invasive stool testing or sigmoidoscopy. However, in both settings, colonoscopy is not fully protective for the occurrence of post-colonoscopy CRCs (PCCRCs).
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Source Type: research
Conclusion: Access to health care in the US is important for KAs to have CRC screening in the US. As medical tourism has been increasing globally, the location of CRC screening utilization must be considered in research on cancer screening to determine correlates of CRC screening. PMID: 29802705 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
Abstract Colorectal cancer is a common cause of morbidity and mortality in the United States. Most colorectal cancers arise from preexisting adenomatous or serrated polyps. The incidence and mortality of colorectal cancer can be reduced with screening of average-risk adults 50 to 75 years of age. Randomized controlled trials show evidence of reduced colorectal cancer-specific mortality with guaiac-based fecal occult blood tests and flexible sigmoidoscopy. There are no randomized controlled trials on the effectiveness of colonoscopy to reduce colorectal cancer-specific mortality; however, several randomized control...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Abstract AIMS: Evaluation of the role and impact of introducing a dedicated coloproctology procedure clinic in tertiary referral colorectal unit. METHODS: A retrospective analysis of 126 consecutive patients managed in the coloproctology clinic between March2015 and September 2016 was carried out. All patients were preselected for attendance based on symptom-based protocol. RESULTS: Based on the information available in GP referrals, 126 patients with bleeding per rectum with low risk of cancer were re-triaged from the general outpatient to dedicated coloproctology procedure clinic. Those patients accoun...
Source: Anal Sci - Category: Chemistry Authors: Tags: Ir J Med Sci Source Type: research
AbstractAimsEvaluation of the role and impact of introducing a dedicated coloproctology procedure clinic in tertiary referral colorectal unit.MethodsA retrospective analysis of 126 consecutive patients managed in the coloproctology clinic between March2015 and September 2016 was carried out. All patients were preselected for attendance based on symptom-based protocol.ResultsBased on the information available in GP referrals, 126 patients with bleeding per rectum with low risk of cancer were re-triaged from the general outpatient to dedicated coloproctology procedure clinic. Those patients accounted for 14% of waiting list....
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
Authors: Bevan R, Rutter MD Abstract Colorectal cancer (CRC) is the third most common cancer worldwide. It is amenable to screening as it occurs in premalignant, latent, early, and curable stages. PubMed, Cochrane Database of Systematic Reviews, and national and international CRC screening guidelines were searched for CRC screening methods, populations, and timing. CRC screening can use direct or indirect tests, delivered opportunistically or via organized programs. Most CRCs are diagnosed after 60 years of age; most screening programs apply to individuals 50-75 years of age. Screening may reduce disease-specific m...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Abstract IntroductionIn the UK Bowel Scope screening programme (BSSP), patients progress to colonoscopy based on high‐risk features on flexible sigmoidoscopy (FS). ObjectiveTo assess practice of colonoscopy conversion and predictors of additional adenoma detection on colonoscopy. DesignThe Bowel Cancer Screening database was interrogated and collated with endoscopic and histological findings from patients undergoing colonoscopy following FS between August 2013 and August 2016. Multivariate analysis was performed to identify predictors of new adenomas. SettingWolverhampton bowel cancer screening centre, covering Wolverham...
Source: Colorectal Disease - Category: Gastroenterology Authors: Tags: Original Article Source Type: research
AbstractSince the invention of endoscopy in the 1800s, colonoscopy and flexible sigmoidoscopy have evolved into important tools in the diagnosis and treatment of lower gastrointestinal luminal diseases. These two modalities along with biochemical markers and widespread implementation of colorectal cancer (CRC) screening are responsible for the overall downtrend of CRC. However, this downward trend is not as robustly reflected in the right-sided CRC. It is thought that flat lesions in the right colon (sessile serrated polyp (SSA/P)), suboptimal colon preparation, differences in gender, and endoscopic techniques are some of ...
Source: Current Colorectal Cancer Reports - Category: Cancer & Oncology Source Type: research
Conclusion: Our CRC prediction model that incorporates more comprehensive family history of CRC can provide improved calibration and discrimination of risks compared with the simple FH model, especially in populations with higher underlying risk. The models developed may potentially further improve screening decision making among subgroups with elevated CRC risk.References:1. Freedman AN, Slattery ML, Ballard-Barbash R, et al. Colorectal cancer risk prediction tool for white men and women without known susceptibility . J Clin Oncol 2009;27(5):686-693.2. Antoniou AC, Pharoah PDP, McMullan G, et al. A comprehensive model for...
Source: Cancer Epidemiology Biomarkers and Prevention - Category: Cancer & Oncology Authors: Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Oral Presentations - Proffered Abstracts Source Type: research
The National Health Service Bowel Cancer Screening Programme (NHS BCSP) offers colonoscopy to people testing positive for Faecal Occult Blood Test (FOBT) after the age of 60. In addition, the 'Bowel scope screening' test offers once-only flexible sigmoidoscopy to people in the UK after the age of 55. The Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening trial in the USA found that flexible sigmoidoscopy is associated with decreased colorectal cancer incidence but used a lower threshold for follow up diagnostic colonoscopy when compared to similar studies in Europe.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Sunday – ASGE poster Source Type: research
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