Identification of phenotypes at risk of transition from diastolic hypertension to isolated systolic hypertension
Identification of phenotypes at risk of transition from diastolic hypertension to isolated systolic hypertension Journal of Human Hypertension advance online publication, September 10 2015. doi:10.1038/jhh.2015.91 Authors: R Esposito, R Izzo, M Galderisi, M De Marco, E Stabile, G Esposito, V Trimarco, F Rozza, N De Luca &G de Simone
HIGH blood pressure means a person's blood pressure is consistently too high and dangerous consequences could ensue. With many on lock down and self-isolating, how can you properly measure your blood pressure without the equipment?
Conditions: Persistent Fetal Circulation; Persistent Pulmonary Hypertension of the Newborn; PPHN Interventions: Drug: Nebulized Magnesium Sulfate; Drug: Intravenous Magnesium Sulfate Sponsor: Sohag University Completed
Conditions: Periodontal Diseases; Gingivitis; Hypertension Interventions: Behavioral: electric toothbrush; Procedure: Professional oral hygiene Sponsor: University of L'Aquila Not yet recruiting
Conditions: Polycystic Ovary Syndrome; Hypertension Interventions: Drug: GnRH antagonist; Drug: GnRH antagonist + MethylTESTOSTERone 5 MG Sponsor: Yale University Enrolling by invitation
This study was designed to investigate the role of long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in the proliferation as well as apoptosis of human umbilical vein endothelial cells (HUVECs), to offer a basis for therapy of hypertension. MATERIAL AND METHODS The lncRNA MALAT1 expression, hsa-miR-124-3p, hsa-miR-135a-5p, hsa-miR-135b-5p, and hsa-miR-455-5p in plasma were measured from 230 patients with hypertension and 230 non-hypertensive controls. The mechanism for lncRNA MALAT1 modulating the proliferation and apoptosis of HUVECs was explored by cell transfection, Cell Counti...
A better understanding of how hypertension control differs between population subgroups may help improve management and reduce disparities.American Journal of Epidemiology
We describe the use of the Impella 5.0 (Abiomed Inc., Danvers, Massachusetts) as a bridge to HeartMate 3 implantation in a highly sensitized patient with severe pulmonary hypertension following the Mustard procedure for TGA.
No abstract available
This study aimed to assess the hemodynamic effects of concomitant MVS. Of all 73 enrolled patients, 44 patients had undergone concomitant MVS and 29 patients had not. Before LVAD implantation, MVS group had higher pulmonary capillary wedge pressure (p = 0.04). After LVAD implantation, MVS group had higher mean pulmonary artery pressure and cardiac output (CO). During the hemodynamic ramp study, MVS group had steeper CO slopes (0.18 [0.13 0.28] vs. 0.15 [0.08, 0.20] L/min/step; p = 0.04) at incremental LVAD speed and achieved a higher CO at the optimized set speed (5.5 [4.7, 6.9] vs. 4.9 [4.0, 5.7] L/min; p = 0.03). One-yea...
Children with end-stage lung failure awaiting lung transplant would benefit from improvements in artificial lung technology allowing for wearable pulmonary support as a bridge-to-transplant therapy. In this work, we designed, fabricated, and tested the Pediatric MLung—a dual-inlet hollow fiber artificial lung based on concentric gating, which has a rated flow of 1 L/min, and a pressure drop of 25 mm Hg at rated flow. This device and future iterations of the current design are designed to relieve pulmonary arterial hypertension, provide pulmonary support, reduce ventilator-associated injury, and allow for more effecti...