Case report: veno-venous ECMO as a bridge to lung transplantation in paraquat poisoning
3 out of 5 stars Successful extracorporeal membrane oxygenation therapy as a bridge to sequential bilateral lung transplantation for a patient after severe paraquat poisoning. Tang X et al. Clin Toxicol 2015 Aug 28 [Epub ahead of print] Abstract Conceptually, extracorporeal membrane oxygenation (ECMO) seems a perfect technique for treating some of the sickest toxicology patients, buying time until failing vital functions can recover. With severe cardiotoxins — for example, calcium channel blockers, beta blockers or bupropion — veno-arterial ECMO can provide complete cardiopulmonary bypass, replacing both cardiac and pulmonary function. In the case of severe poisoning with paraquat — a highly toxic herbicide that causes progressive respiratory failure and irreversible pulmonary fibrosis — veno-venous ECMO can replace support pulmonary function and serve as a bridge to lung transplantation. This paper from Beijing Chao-Yang Hospital describes what is, to my knowledge, the first case in which v-v ECMO has been used successfully to treat paraquat poisoning. A 24-year-old, 53-kg woman ingested an estimated 50 ml of 20% paraquat.She arrived at hospital 2 hours later and was initially treated with gastric lavage, laxatives, and activated charcoal. Additional treatment included cyclosphophamide, steroids, and hemoperfusion. Unfortunately, her initial signs and symptoms are not well-described. Three days after presentation, the patie...
Publication date: Available online 17 December 2018Source: Materials Research BulletinAuthor(s): Samatha Benedict, Navakanta BhatAbstractIn this work,we report a novel method for recovery of sulphur poisoned platinum/platinum oxide (Pt-PtOx) core-shell nanowire sensor using UV irradiation.The optimum core to shell thickness ratio and the operating conditions are the key factors to achieve a high-performance H2S sensor,described in this report.The fabricated core-shell nanowire sensor demonstrated response of 6.4% at 1 ppm H2S with detection limit of 10 ppb at 150 °C operating temperature. The senso...
Cape Breton and Moncton had the most people in Atlantic Canada showing up at the hospital with opioid poisoning in 2017, according to a new study by the Canadian Institute for Health Information.
(University of York) Scientists have deciphered how some types of 'swimming' bacteria have evolved to be able to escape when trapped in small spaces.The discovery could pave the way to finding new methods to stop the spread of certain bacteria, including species that cause food poisoning and stomach ulcers.
This article aims to provide a brief overview of the technical aspects and the potential indications and limitations of the different ECTRs, highlighting the important characteristics of poison amenable to ECTR and the most appropriate prescriptions used in the setting of acute poisoning. The various principles that govern poison elimination by ECTR (diffusion, convection, adsorption, and centrifugation) and how components of the ECTR can be adjusted to maximize clearance have also being discussed.
MILWAUKEE - A federal judge in Wisconsin on Nov. 2 ruled that Armstrong Containers Inc. is the successor-in-interest to a previous maker of lead-based paint and that the asset sale agreement Armstrong made with a third entity involved an assumption of obligations related to any judgment involved in lead-poisoning litigation (Glenn Burton v. American Cyanamid, et al., No. 07-0303, E.D. Wis.).
ANNAPOLIS, Md. - In an unpublished opinion, a panel of the Maryland Court of Special Appeals on Nov. 9 ruled that a man who was a representative for the owner of a property could not be held liable for a tenant's lead-paint poisoning because the record does not show any evidence that the representative was involved in the day-to-day operations of the property (Markeys A. Stedman v. Ian David Turk, No. 1108, Sept. Term 2016, Md. Spec. App., 2018 Md. App. LEXIS 1022).
When someone has food poisoning, they may want to limit themselves to a bland diet to avoid irritating the stomach further. Many people recommend the BRAT diet as a good one to follow after food poisoning. Learn more about the best foods and drinks to consume and avoid after food poisoning here.
Conclusions: We identified novel toxins and proteins from R. schneideri mucous glands. Besides, this is a pioneer study that presented the in depth characterization of protein molecules richness from this toad secretion. The results obtained herein showed evidence of novel AMP and enzymes that need to be further explored.
Publication date: Available online 15 December 2018Source: Food ChemistryAuthor(s): Pablo Estevez, David Castro, J. Manuel Leao, Takeshi Yasumoto, Robert Dickey, Ana Gago-MartinezAbstractThe increased emergence of Ciguatera Fish Poisoning in the Canary Islands and Madeira demanded the development of confirmatory methods by liquid chromatography coupled to tandem mass spectrometry to characterize the risk. Efforts were particularly focused on the optimization of sample pretreatment, especially in the sample cleanup step, to efficiently remove matrix interferences as a critical factor to consider in mass spectrometry detecti...
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