Case report: veno-venous ECMO as a bridge to lung transplantation in paraquat poisoning

3 out of 5 stars Successful extracorporeal membrane oxygenation therapy as a bridge to sequential bilateral lung transplantation for a patient after severe paraquat poisoning. Tang X et al.  Clin Toxicol 2015 Aug 28 [Epub ahead of print] Abstract Conceptually, extracorporeal membrane oxygenation (ECMO) seems a perfect technique for treating some of the sickest toxicology patients,  buying time until failing vital functions can recover. With severe cardiotoxins — for example, calcium channel blockers, beta blockers or bupropion — veno-arterial ECMO can provide complete cardiopulmonary bypass, replacing both cardiac and pulmonary function. In the case of severe poisoning with paraquat — a highly toxic herbicide that causes progressive respiratory failure and irreversible pulmonary fibrosis — veno-venous ECMO can replace support pulmonary function and serve as a bridge to lung transplantation. This paper from Beijing Chao-Yang Hospital describes what is, to my knowledge, the first case in which v-v ECMO has been used successfully to treat paraquat poisoning. A 24-year-old, 53-kg woman ingested an estimated 50 ml of 20% paraquat.She arrived at hospital 2 hours later and was initially treated with gastric lavage, laxatives, and activated charcoal. Additional treatment included cyclosphophamide, steroids, and hemoperfusion. Unfortunately, her initial signs and symptoms are not well-described. Three days after presentation, the patie...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical ECMO extracorporeal membrane oxygenation lung transplantation paraquat poisoning Source Type: news

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Cape Breton and Moncton had the most people in Atlantic Canada showing up at the hospital with opioid poisoning in 2017, according to a new study by the Canadian Institute for Health Information.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Nova Scotia Source Type: news
(University of York) Scientists have deciphered how some types of 'swimming' bacteria have evolved to be able to escape when trapped in small spaces.The discovery could pave the way to finding new methods to stop the spread of certain bacteria, including species that cause food poisoning and stomach ulcers.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
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Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - Category: Medical Law Source Type: news
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Source: LexisNexis® Mealey's™ Emerging Toxic Torts Legal News - Category: Medical Law Source Type: news
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Source: Health News from Medical News Today - Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news
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