A Medical Mockery – 10 healthcare adverts that show just how far we’ve come!

The post A Medical Mockery – 10 healthcare adverts that show just how far we’ve come! appeared first on Hysterectomy Association. You don’t have to look far to hear about brilliant and exciting strides being made in medical science. 3D printing is being used to create artificial limbs and organs; diabetics can now control their condition with the artificial pancreas; news has broken in 2015 about revolutionary new treatments which provide hope for patients with skin cancer and Alzheimer’s disease. These outstanding breakthroughs are in fact part of a much bigger picture – our attitudes towards health, and our understanding of even relatively minor ailments like indigestion, headaches and insomnia have come on in leaps and bounds because of ongoing Clinical Trials like the ones carried out at Covance in Leeds. Perhaps treatments for period pain or body odour don’t grab the most front-page headlines, but a look at how medicines have been advertised over the last hundred years speaks volumes about just how far we’ve come and these 10 healthcare adverts illustrate that beautifully… 1 – La-Mar Reducing Soap A soap bar which washes away fat!? A dream come true, or too good to be true? (The global obesity epidemic suggests the latter!). In this brazen advert,  La-Mar Laboratories confidently assert that this product works ‘like magic’ to produce results which are ‘quick and amazing’, even statin...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Latest News covance medical adverts Source Type: news

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In conclusion, BLU-5937 was selected as a drug candidate for the treatment of chronic cough due to its high potency and selectivity for P2X3 homotrimeric receptors, strong anti-tussive effects, excellent tolerability and predicted pharmacokinetic properties in humans.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research
ConclusionsThese findings indicate that the neural effects of AUD vary according to severity. Our results emphasize the utility of resting state fMRI as a neuroimaging biomarker for quantitative clinical evaluation of AUD.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Publication date: Available online 19 March 2019Source: NeuroImage: ClinicalAuthor(s): Jason A. Martin, Nadine Zimmermann, Lukas Scheef, Jakob Jankowski, Sebastian Paus, Hans H. Schild, Thomas Klockgether, Henning BoeckerAbstractMany studies have used functional magnetic resonance imaging to unravel the neuronal underpinnings of motor system abnormalities in Parkinson's disease, indicating functional inhibition at the level of basal ganglia-thalamo-cortical motor networks. The study aim was to extend the characterization of functional motor changes in Parkinson's Disease by dissociating between two phases of action (i.e. m...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Publication date: August 2019Source: Current Opinion in Behavioral Sciences, Volume 28Author(s): Bianka Karshikoff, Melissa Anne Tadros, Sean Mackey, Ihssane ZouikrToday’s treatment for chronic pain is inadequate, and novel targets need to be identified. This requires a better understanding of the mechanisms involved in pain sensitization and chronification. In this review, we discuss how peripheral inflammation, as occurs during an infection, modulates the central pain system. In rodents, neonatal inflammation leads to increased pain sensitivity in adulthood by priming immune components both peripherally and central...
Source: Current Opinion in Behavioral Sciences - Category: Psychiatry & Psychology Source Type: research
ConclusionsFOSL1 is an independent prognostic biomarker of GC. Detecting FOSL1 expression could help stratify GC patients with high-risk and guide the precious treatment.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
In this study, we aimed to investigate the role of IL-6/Stat3 signaling pathway in human endometrial cancer cells invasion and migration. We demonstrated that Stat3 is activated in endometrial cancer cell lines. To investigate the role of Stat3 in endometrial cancer invasive capacity, we used Stat3 inhibitor Stattic and found that Stattic significantly inhibited the migration and invasion of endometrial cancer cells elevated by IL-6. Furthermore, we showed that Stat3 inhibitor significantly decreased the expression of MMP2 enhanced by IL-6, indicating that IL-6 promoted endometrial cancer invasion and migration by Stat3-in...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 19 March 2019Source: Pathology - Research and PracticeAuthor(s): Xiaobo He, Ying ShuAbstractIncreasing evidence has shown that dysregulation of mircoRNA (miRNA) is linked to the development and progression of human cancer, including gastric cancer (GC). In the current study, by analysing the GEO database (GSE78091), we found that miR-660 was significantly downregulated in GC. Consistently, quantitative real-time PCR (qRT-PCR) results showed that miR-660 was dramatically decreased in GC tissues and cell lines. Importantly, low miR-660 expression was closely related to larger tumor size (P&...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
ConclusionsThe results pointed out that the high expression of miR-106b-5p serves as an independent factor for predicting the worse prognosis of RCC patients.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 20 March 2019Source: The Journal of Foot and Ankle SurgeryAuthor(s): J. Randolph Clements, Ajay K. GhaiAbstractDisruption of the plantar plate is a common cause of forefoot pain, metatarsalgia, and metatarsophalangeal joint malalignment. Although surgical repair of the plantar plate has improved, there has been no consensus on the clinical superiority of any single technique, or combination of techniques, described in the literature to date. In this publication, we report a case of plantar plate injury treated with an innovative new technique with 20-month follow-up.
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
We report a case of a 48-year-old female who presented four months following a low-energy trauma with symptoms most consistent with adhesive capsulitis. An MRI demonstrated extensive patchy areas of intramuscular edema-like signal involving the lateral head of the deltoid with associated muscle atrophy, in keeping with a subacute denervation injury. She was diagnosed with quadrilateral space syndrome (QSS) and successfully treated with an fluoroscopic-guided corticosteroid injection. At her two-year follow-up, the patient had regained full function and had no lasting symptoms. Non-specific symptoms like ill-defined shoulde...
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
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