Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice
Conclusions
These findings suggest that specific enhancement of the pFlux for small organic solutes across the claudin-based TJs initiates colonic inflammation.
Source: Gut - Category: Gastroenterology Authors: Tanaka, H., Takechi, M., Kiyonari, H., Shioi, G., Tamura, A., Tsukita, S. Tags: Inflammatory bowel disease Source Type: research
More News: Gastroenterology | Inflammatory Bowel Disease