Serious As A Heart Attack

Did you know that unless you do something about it, you’ll lose a third of your heart muscle as you age?1 Your heart muscle cells are very high-energy and burn a lot of metabolic fuel. After they burn the fuel, like with anything that produces energy, there’s some waste left over. In your heart, that [...]Related Posts:Serious as a heart attackPower To Penetrate
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Heart Health Newsletter omega-3s telomeres Source Type: news

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In this study, mature DCs (mDCs), generated from the GM-CSF and IL-4 induced bone marrow cells, were intravenously injected into wild-type mice. Three days later, assays showed that the mDCs were indeed able to return to the thymus. Homing DCs have been mainly reported to deplete thymocytes and induce tolerance. However, medullary TECs (mTECs) play a crucial role in inducing immune tolerance. Thus, we evaluated whether the mDCs homing into the thymus led to TECs depletion. We cocultured mDCs with mTEC1 cells and found that the mDCs induced the apoptosis and inhibited the proliferation of mTEC1 cells. These effects were onl...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Having trouble viewing this email? View it as a Web page. NIDCR's Fall 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities &Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   NIDCR News 5 Q&As About “Oral Health in America: Advances and Challenges” NIDCR issued a brief Q&A regarding details of the forthcoming report Oral Health in America: Advances and Challenges, which will be published in Fall 2021. This comprehensive report will examine improvements in oral health over the past t...
Source: NIDCR Science News - Category: Dentistry Source Type: news
In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF-1 levels and clinical disease. We examined prospective associations of serum IGF-1 with mortality, dementia, vascular disease, diabetes, osteoporosis, and cancer, finding two generalized patterns. First, IGF-1 interacts with age to modify risk in a manner consistent with antagonistic pleiotropy; younger individuals with high IGF-1 are protected from disease, while older individuals with high IGF-1 are at increased risk for incident disease or death. Second, the association between IGF-1 and risk ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
AbstractBackgroundRecent research shows AKI increases the risk of incident CKD. We hypothesized that perioperative AKI may confer increased risk of subsequent CKD compared to nonperioperative AKI.MethodsA MEDLINE search was performed for “AKI, CKD, chronic renal insufficiency, surgery, and perioperative” and related terms yielded 5209 articles. One thousand sixty-five relevant studies were reviewed. One thousand six were excluded because they were review, animal, or pediatric studies. Fifty-nine studies underwent full manuscript review by two independent evaluators. Seventeen met all inclusion criteria and unde...
Source: Perioperative Medicine - Category: Surgery Source Type: research
Transcatheter mitral valve (MV) repair with MitraClip (Abbott Vascular, Santa Clara, California) is an established treatment in patients with severe mitral regurgitation (MR) at inoperable or high surgical risk. Acute ischemic MR can occur due to leaflet tethering or papillary muscle dysfunction secondary to acute myocardial infarction (AMI), leading to cardiogenic shock or congestive heart failure.1-3 While MV surgery has been the mainstay for acute ischemic MR refractory to medical treatment,1 recent reports have shown the feasibility of MitraClip in selected patients with acute/subacute MR following AMI.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
J Thorac Dis. 2021 Mar;13(3):1899-1908. doi: 10.21037/jtd-20-1819.ABSTRACTCoronary artery bypass grafting is the most common cardiac surgical procedure performed worldwide and the long saphenous vein the most common conduit for this. When performed as an open vein harvest (OVH), the incision on each leg can be up to 85cm long, making it the longest incision of any routine procedure. This confers a high degree of morbidity to the procedure. Endoscopic vein harvest (EVH) methods were popularised over two decades ago, demonstrating significant benefits over OVH in terms of leg wound complications including surgical site infec...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Authors: Source Type: research
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