X chromosome gain in male breast cancer
Male breast cancer (MBC) is an uncommon disease whose molecular profile is not well known. X chromosome gain has been described as a marker of aggressive behavior in female breast cancer. The aim of this study is to investigate the role of the X chromosome in male breast cancer. 20 cases of male breast invasive ductal carcinoma were retrieved and compared with 10 cases of gynecomastia. Cases were tested by fluorescence in situ hybridization (FISH) in order to assess a cytogenetic profile for the X chromosome.
Source: Human Pathology - Category: Pathology Authors: Enrico Di Oto, Valentina Monti, Maria C. Cucchi, Riccardo Masetti, Zsuzsanna Varga, Maria P. Foschini Tags: Original contribution Source Type: research
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