Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines
Conclusion:
AARS, AURKA, AURKB, CENPA, CCNB1, CCNE2, and CDK may contribute to MTX resistance via aminoacyl-tRNA biosynthesis pathway, cell cycle pathway, or p53 signaling pathway.
Source: Journal of Orthopaedic Surgery and Research - Category: Orthopaedics Authors: Xiao-rong YangYan XiongHong DuanRen-rong Gong Source Type: research
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