Soluble Dextrin Fibers Alter the Intestinal Microbiota and Reduce Proinflammatory Cytokine Secretion in Male IL-10-Deficient Mice [Nutrition and Disease]

Conclusions: These results demonstrate that soluble prebiotic fibers selectively stimulate the growth of a distinctive gut microbiota in IL-10–/– mice. SFD-t induced the growth of butyrate-producing microbes and was effective in reducing proinflammatory cytokine secretion and enterocyte injury in this mouse model of colitis.

Source: Journal of Nutrition - September 1, 2015 Category: Nutrition Authors: Valcheva, R., Hotte, N., Gillevet, P., Sikaroodi, M., Thiessen, A., Madsen, K. L. Tags: Nutrition and Disease Source Type: research