The proinflammatory cytokine, interleukin-17A, augments mitochondrial function and neurite outgrowth of cultured adult sensory neurons derived from normal and diabetic rats.

CONCLUSIONS: IL-17A enhanced axonal plasticity through activation of ERK and PI-3K pathways and was associated with augmented mitochondrial bioenergetics function in sensory neurons. PMID: 26321687 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26321687?dopt=Abstract

Source: Experimental Neurology - August 27, 2015 Category: Neurology Authors: Habash T, Saleh A, Roy Chowdhury SK, Smith DR, Fernyhough P Tags: Exp Neurol Source Type: research