At What Level Does Elevated Glucose Cause Glucosuria?

Discussion Constipation generally is defined as infrequent or painful defecation. Most children develop constipation after the child begins to associate pain (e.g. a hard bowel movement) with defecation. The child then begins to withhold the stools trying to decrease the defecation discomfort. As stool withholding continues, the rectum dilates and gradually accommodates with the normal defecation urge disappearing. Passing large hard stools infrequently reinforces the defecation pain. The cycle continues. If the cycling is severe enough, worsening stool retention and more abnormal defecation dynamics occurs. Chronic rectal distension results in both loss of rectal sensitivity, and loss of urge to defecate, which can lead to encopresis. The differential diagnosis of constipation can be reviewed here. Constipation can also lead to enuresis because of increased pressure on the bladder and also because of inappropriate toileting behaviors where children infrequently voids as well as defecates. The differential diagnosis of diurnal enuresis can be reviewed here. Type 1 diabetes mellitis is one of the most common chronic diseases in childhood and is increasing in prevalence worldwide. In childhood the presentation age is bimodal with one peak at 4-6 years and another at 10-14 years. Most studies show no gender differences except for an increase in older adolescent males noted in European studies. The diagnosis is made by a fasting glucose of> 126 mg/dL (7 mmol), or postprandial...
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