Inspiring video of a double lung transplant survivor
Here is a inspiring video of my 35 year old brother who has Cystic Fibrosis and had a double lung transplant 5 years ago. This video was made to document the celebration of the 5 years and to reflect on his life so far. http://youtu.be/OBk_1h3CK-g Or search LUNGIVERSARY on YouTube. Please comment and share if you enjoyed it
A pediatric patient with cystic fibrosis and a double-lung transplant received a genetically engineered 3-phage cocktail to treat a life-threatening antibiotic-resistant Mycobacterium abscessus infection for which all standard therapeutic options had been exhausted. Over 7 months of twice-daily intravenous infusions, as well as daily topical phage therapy, the 15-year-old patient ’s surgical wound and skin lesions healed gradually and her lung and liver function improved. No adverse reactions to the treatment were reported.
Conclusion: These results demonstrate the high prevalence of extrapulmonary comorbidities in transplanted CF adult patients particularly CFRD. We highlight the need for specific surveillance and prevention for transplanted CF patients who were already treated for extra espiratory comorbidities before lung transplantation, due to the potential aggravation of their comorbidities after transplantation. PMID: 31267788 [PubMed - as supplied by publisher]
Since lung transplantation became a viable option for cystic fibrosis (CF) lung disease, adult transplant recipients with CF have superior survival compared to all the other major diagnostic indications. However, among adults, recipients with CF have a younger age at transplant in comparison to other transplant recipients. Over time, the frequency and proportion of lung transplants for CF has increased for adults in comparison to children. Using a large international transplant registry, we investigated time trends in numbers of transplants, age at transplant, and post-transplant survival and cause of death for recipients with CF.
New variables ID the sickest waitlist candidates with cystic fibrosis, chronic obstructive pulmonary disease
Elizabeth Dolan, 28, was never expected to live past age 10 due to her incurable lung condition. On February 1, she got a double lung transplant in California and is breathing easier than ever.
(Cleveland Clinic) Implemented in 2005, the lung allocation score is used to prioritize patients awaiting lung transplants in the US. Sicker transplant candidates have a higher calculated score and are placed at the top of the list. But a recent study led by Maryam Valapour, M.D., MPP, director of Lung Transplant Outcomes in Cleveland Clinic's Respiratory Institute, found including new clinical variables helped to better identify the sickest cystic fibrosis and chronic obstructive pulmonary disease patients awaiting transplants.
We describe the use of transnasal humidified rapid-insufflation ventilatory exchange for deep sedation during dental extractions in a patient with severe cystic fibrosis as a precondition for lung transplantation. Patient wanted to have the procedure under general anesthesia with intubation due to extreme anxiety. However, we advocated deep IV sedation with transnasal humidified rapid-insufflation ventilatory exchange. Oxygenation was maintained without airway obstruction and pulmonary complications during the entire procedure of 110 minutes.
CONCLUSIONS: Adding CF-specific variables improved discrimination among waitlisted CF candidates, and benefitted COPD candidates. PMID: 31199166 [PubMed - as supplied by publisher]