Acute kidney injury: IL-34 promotes persistent ischaemia-induced AKI

Nature Reviews Nephrology 11, 504 (2015). doi:10.1038/nrneph.2015.116 Author: Jessica K. Edwards Colony stimulating factor 1 (CSF-1) is central to macrophage-mediated renal repair during inflammation, but little is known about the function of IL-34, with which it shares a receptor (c-FMS). Now, data from Vicki Rubin Kelley and colleagues support a mechanism by which macrophages can promote
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research