Independent association between brachial-ankle pulse wave velocity and global longitudinal strain of left ventricle
This study was performed to investigate the association between brachial-ankle pulse wave velocity (baPWV) and LV global longitudinal strain (GLS). A total of 248 subjects (mean age 59.2 ± 12.3 years; 50 % were men) without structural heart problems were retrospectively evaluated. LV GLS was measured by 2-dimensional speckle-tracking echocardiography. baPWV measurements were made on the same day of echocardiography. The incidences of hypertension, diabetes mellitus, and dyslipidemia were 51.2, 19.4, and 22.2 %, respectively. The mean value of baPWV was 1557 ± 285 cm/s. In simple linear regression analysis, baPWV had a significant positive association with LV GLS (β = 0.215, P = 0.001). In multiple linear regression analysis, baPWV was independently associated with LV GLS even after controlling for potential confounders, including age, gender, body mass index, systolic blood pressure, heart rate, HbA1c, total cholesterol, estimated glomerular filtration rate, left ventricular mass index, E/A, septal e′ velocity and pulmonary artery systolic pressure (β = 0.211, P = 0.028). The results of this study suggest that baPWV may be independently associated with LV GLS, supporting the evidence of a close interaction between arterial stiffness and LV function. Increased arterial stiffness may result in impaired LV longitudinal function.
An 85-year-old man presented with left hemiparesis, too late for any intervention. Brain computed tomography (CT) revealed a right hemispheric infarct. He had a history of diabetes mellitus (on metformin, statin), hypertension (on losartan/lercanidipine), past smoking, COPD (on inhalers) and peripheral artery disease (on aspirin).
(Natural News) Heart disease and cerebrovascular diseases (e.g., stroke) are the leading causes of death in western countries. These diseases are caused by several factors, such as hypertension, high blood cholesterol, diabetes mellitus, smoking and obesity. However, recent studies have found that there is another unexpected contributor to the development of atherosclerosis and atherothrombosis (blood clot...
Conclusions: CV risk calculations revealed higher than rates than expected with consequently reflected on higher than estimated CVRAS. This represents the first report of its kind in Honduras.
AbstractIntroductionOverweight and obesity are increasing worldwide and are associated with an increased risk for cardiovascular disease (CVD). The aim of this study was to examine the burden of CVD risk factors among normal weight, overweight, and obese subjects with hypertension, and to evaluate the effectiveness of switching to a single-pill combination (SPC) of perindopril arginine/indapamide for blood pressure (BP) control in overweight and obese subjects treated in routine clinical practice.MethodsFORSAGE was a 3-month, multicenter, observational, open-label study conducted in Russian patients with uncontrolled arter...
ConclusionsA potent risk predictive model was established, which is of great value for the secondary prevention of diabetes. Weight loss, lowering of SBP and blood uric acid levels and appropriate control for DBP may significantly reduce the risk of new-onset ACS in T2DM patients in Northwest China.
ConclusionsIn this high-risk, low-income cohort, contributions of risk factors to HF varied, particularly by race. To reduce the population burden of HF, interventions tailored for specific race and sex groups may be warranted.Central Illustration
ConclusionOur findings provide a new insight into the prediction for restenosis in CHD patients underwent PCI with SES.
Conclusion: There was a high prevalence of MetS and abnormal ECG among the studied population. Abnormal ECG findings were more common in men with no differential association in people with or without MetS. However, a significant association existed between certain components of MetS and ECG abnormalities in men only. Male gender and HDLc were independent predictors of ECG Abnormalities.Keyword: Electrocardiography, metabolic syndrome, africans.
This study aimed to investigate the irisin levels in elderly patients with hypertension, diabetes mellitus type 2, and overweight and obesity, to investigate the possible association between irisin levels and anthropometric and biochemical parameters, and also to assess the irisin levels associated with a risk of hypertension, diabetes mellitus type 2, and overweight and obesity.MethodsA nested case-control study was conducted, with hypertension, diabetes mellitus type 2, and overweight and obesity being set as the case group; 71 elderly patients from the cohort were enrolled in each case group, and 71 healthy elderly from...
CONCLUSIONS: More than half of T2DM patients in North China had poor glycemic control and were at a higher risk of developing diabetic complications. The EN and machine learning algorithms are alternative choices, in addition to the traditional logistic model, for building predictive models of blood glucose control in patients with T2DM. PMID: 31923100 [PubMed - in process]