Why President Carter's Melanoma Announcement Was Groundbreaking

Former President Jimmy Carter announced in a press conference Thursday that cancer has spread to his brain, and that he will be receiving radiation over the next few months to treat it.  With candor that's typical for Carter, but remarkable compared to how other American presidents have announced illnesses, the former president described that he first sought treatment for a bad cold in May. Instead, doctors found a mass on his liver that turned out to be melanoma. Surgeons removed the cancer, as well as about one-tenth of his liver, in an operation August 3, but discovered that the cancer had spread to his brain. These four lesions, measuring about two millimeters, were treated with radiation on August 20 and then again every three weeks. Carter is also receiving a drug that enhances his immune system.  “I’m perfectly at ease with whatever comes,” said Carter. “I do have deep religious faith, which I’m very grateful for, and I was pleasantly surprised that I didn’t go into an attitude of despair or anger or anything like that. I was just completely at ease. “I’m looking forward to a new adventure,” he added.  (function(){var src_url="https://spshared.5min.com/Scripts/PlayerSeed.js?playList=519027675&height=381&width=570&sid=577&origin=SOLR&videoGroupID=155847&relatedNumOfResults=100&responsive=false&relatedMode=2&relatedBottomHeight=60&companionPos=&hasCompanion=false&autoStart=false&colorPallet=%23FFEB...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Publication date: Available online 25 May 2019Source: Preventive MedicineAuthor(s): Abbey E. Poirier, Yibing Ruan, Karena D. Volesky, Will D. King, Dylan E. O'Sullivan, Priyanka Gogna, Stephen D. Walter, Paul J. Villeneuve, Christine M. Friedenreich, Darren R. Brenner, ComPARe Study Team
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 20 May 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): Alessandro de Sire, Marco Invernizzi, Lorenzo Lippi, Carlo Cisari, Levent Özçakar, Franco Franchignoni
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: Available online 25 May 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Roy Lauterbach, Susana Mustafa-Mikhail, Emad Matanes, Amnon Amit, Zeev Wiener, Lior LowensteinAbstractObjectivesThe purpose of this study was to compare the learning curves, surgical outcomes and complications of multi-port access robotic-assisted laparoscopic sacrocervicopexy (MP-RSC) to single-port robotic access (SP-RSC) for vaginal apex prolapse.MethodsA retrospective study of the first 52 MP-RSC procedures compared with the first 52 SP-RSC procedures performed at one medical center. P...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Publication date: Available online 25 May 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Elisabeth Reiser, Stefanie Aust, Veronika Seebacher, Alexander Reinthaller, Hannah von Mersi, Richard Schwameis, Stephan Polterauer, Christoph Grimm, Samir Helmy-BaderAbstractObjectiveGamma-glutamyltransferase (GGT) is involved in tumor development, progression and chemotherapy resistance. The present study evaluated GGT serum levels as a preoperative predictive marker for ovarian cancer in patients with adnexal mass.Study DesignPreoperative GGT serum levels of 2235 patients with adnexal m...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Publication date: Available online 25 May 2019Source: Leukemia Research ReportsAuthor(s): Aya Nakaya, Shinya Fujita, Atsushi Satake, Takahisa Nakanishi, Yoshiko Azuma, Yukie Tsubokura, Ryo Saito, Akiko Konishi, Masaaki Hotta, Hideaki Yoshimura, Kazuyoshi Ishii, Tomoki Ito, Shosaku Nomura
Source: Leukemia Research Reports - Category: Hematology Source Type: research
Publication date: Available online 25 May 2019Source: Leukemia Research ReportsAuthor(s): Jihane Belkhair, Abderahim Raissi, Hicham Elyahyaoui, Mustapha Ait Ameur, Mohamed ChakourAbstractAtypical chronic myeloid leukemia (aCML), BCR-ABL1 negative is a rare myelodysplastic syndrome /myeloproliferative neoplasm for which no current standard of care exists. The blood smear of patients with aCML showed prominent immature granulocytosis, and granulocytic dysplasia. We admitted a 58-year-old man with splenomegaly, hyperleukocytosis, anemia, and thrombocytopenia; then cytology, cytogenetic and molecular biology analysis of bone m...
Source: Leukemia Research Reports - Category: Hematology Source Type: research
ConclusionIn this study, no significant association was observed between visceral obesity and the number of metastatic lymph node, nor with survival at 5 and 10 years.ResumoIntroduçãoA presença de metastização ganglionar no câncer colorretal é determinante como fator de prognóstico e para planear o tratamento. A relação entre a presença de gordura visceral e o prognóstico não está totalmente documentada na literatura. Assim, pretende-se avaliar a existência de relação entre obesidade visceral e a presen&cced...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
Publication date: Available online 25 May 2019Source: Pharmacological ResearchAuthor(s): František Zálešák, David Jean-Yves Denis Bon, Jiří PospíšilAbstractLignans and neolignans are plant secondary metabolites derived from the oxidative coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from antioxidant, antitumor (terminaloside P, IC50 = 10 nM), anti-inflammatory, anti-neurodegenerative (schibitubin B, IC50 = 3.2 nM) and antiviral (patentiflorin A, IC50 = 14-23 nM) to antimicrobial. In addition, it was observed that several members of thi...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 25 May 2019Source: Journal of Pharmaceutical AnalysisAuthor(s): Jiawei Ye, Mingcheng Xu, Xueke Tian, Sheng Cai, Su ZengAbstractMicroRNAs (miRNAs) are a family of endogenous, small (approximately 22 nucleotides in length), noncoding, functional RNAs. With the development of molecular biology, the research of miRNA biological function has attracted significant interest, as abnormal miRNA expression is identified to contribute to serious human diseases such as cancers. Traditional methods for miRNA detection do not meet current demands. In particular, nanomaterial-based methods, nucleic acid...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
Publication date: August 2019Source: Biomedicine &Pharmacotherapy, Volume 116Author(s): Yu Zheng, Ting Lan, Di Wei, Geng Zhang, Guangdong Hou, Jiarui Yuan, Fei Yan, Fuli Wang, Ping Meng, Xiaojian Yang, Guo Chen, Zheng Zhu, Zifan Lu, Wei He, Jianlin YuanAbstractRenal cell carcinoma (RCC) has always been considered resistant to chemotherapy. IR-780 is a near-infrared fluorescent (NIRF) dye that can be efficiently taken up by RCC cells. Cabazitaxel is a cytotoxic drug that interferes with mitosis by acting on tubulin. We chemically fused IR-780 and cabazitaxel into a new drug, Caba-780, which is expected to increase the s...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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