Child with acute methotrexate related neurotoxicity: Can diffusion weighted MRI help??

Conclusion Methotrexate can result in reversible neurotoxicity in the form of white matter injury. DWI may be used in early detection of such changes; therefore, it provides a rapid, noninvasive readily available tool by which neurotoxicity can be early detected and treated. It has the potential to alert the oncologist to this event and provide a technique by which neurotoxicity can be monitored.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research