MRI scans can deliver cancer therapy

A hospital scan normally used to detect cancer could be used to steer tumour killing treatments to hard-to-reach targets in the body, say scientists.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news

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In conclusion, the synthesized DOX@nanocomposite can be applied in theranostic applications and anticancer drug delivery owing to admissible properties. PMID: 30307331 [PubMed - as supplied by publisher]
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
bin Yin Jian Ni Sustained-release preparation is a hot spot in antitumor drug research, where the first task is to select suitable drug carriers. Research has revealed that carboxylic acid iron metal–organic frameworks (MOFs), constructed from iron (Fe) ions and terephthalic acid, are nontoxic and biocompatible. Due to the breathing effect, the skeleton of this mesoporous material is flexible and can reversibly adapt its pore size through drug adsorption. Therefore, we chose one kind of Fe-MOF, MIL-53(Fe), as a carrier for the anticancer drug oridonin (Ori). In this work, we report the design and synthesis ...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Publication date: 1 January 2019Source: Materials Science and Engineering: C, Volume 94Author(s): Lijun You, Xiaocui Liu, Zhexiang Fang, Qianhui Xu, Qiqing ZhangAbstractA new folic acid (FA)-conjugated poly (lactic-co-glycolicacid) (PLGA)-polyethylene glycol (PEG) nano-noisome was prepared. The noisome was employed as a drug delivery system to load curcumin (Cur) as a model drug and fluorescent probe for cervical cancer therapy and cell imaging. The Fe3O4@PLGA-PEG@FA noisomes were prepared through facile emulsion solvent evaporation and conjugation chemistry method, possessing the properties of high rapid magnetic separati...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
AbstractPurpose of ReviewLung cancer is increasingly a disease of the elderly. Historically, the information on how best to treat these patients is scant, but over recent years, there have been increasing data to support both systemic and targeted treatment as would be offered to younger patients. This paper aims to summarise the considerations behind this.Recent FindingsThe introduction of a screening tool to help understand the overall health of patients will ensure that older cancer patients are considered for all active anti-cancer therapies. These geriatric assessment tools include several important domains such as nu...
Source: Current Geriatrics Reports - Category: Geriatrics Source Type: research
Scientists at the Eunice Kennedy Shriver National Institute for Child Health and Human Development (NICHD) have developed a method implemented as pulse sequences and software to be used with magnetic resonance imaging (MRI) scanners and systems. This technology is available for licensing and commercial development. The method allows for measuring and mapping features of the bulk or average apparent diffusion coefficient (ADC) of water in tissue – aiding in stroke diagnosis and cancer therapy assessment. The pulse sequences and software enable MRI scanners to yield diffusion weighted images (DWI) that are orientationa...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
In conclusion, we visualized that the synthesized DTX-nanomicelles can be used as an anticancer drug delivery system considering their useful biocompatibility and excellent physicochemical properties.Graphical abstract
Source: European Polymer Journal - Category: Chemistry Source Type: research
AbstractPurpose of ReviewLung cancer is increasingly a disease of the elderly. Historically, the information on how best to treat these patients is scant, but over recent years, there have been increasing data to support both systemic and targeted treatment as would be offered to younger patients. This paper aims to summarise the considerations behind this.Recent FindingsThe introduction of a screening tool to help understand the overall health of patients will ensure that older cancer patients are considered for all active anti-cancer therapies. These geriatric assessment tools include several important domains such as nu...
Source: Current Geriatrics Reports - Category: Geriatrics Source Type: research
PET scans with the radiotracer F-18 fluorothymidine (FLT) can help determine...Read more on AuntMinnie.comRelated Reading: SNMMI: PET, MRI may predict pediatric brain tumor outcomes FDG-PET/CT beats FLT-PET/CT for differentiated thyroid cancer FLT-PET could help predict outcome in head and neck cancer JNM: FLT-PET aids prognosis of glioma patients FLT-PET helps predicts cancer therapy results
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Publication date: Available online 23 July 2018Source: International Journal of PharmaceuticsAuthor(s): Mona Alibolandi, Fazileh Hoseini, Marzieh Mohammadi, Pouria Ramezani, Elham Einafshar, Seyed Mohammad Taghdisi, Mohammad Ramezani, Khalil AbnousAbstractGold NPs have great potential in biomedical applications. PAMAM dendrimers are spherical, hyper branched macromolecules which can encapsulate therapeutic molecules while stabilizing metal nanoparticle such as gold NPs. The aim of the current study was to investigate the theranostic capability of curcumin-loaded dendrimer-gold hybrid structure.Dendrimer-gold hybrid structu...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Authors: Kuljittichanok D, Diskul-Na-Ayudthaya P, Weeraphan C, Chokchaichamnankit D, Chiablaem K, Lirdprapamongkol K, Svasti J, Srisomsap C Abstract The incidence rate of hepatocellular carcinoma (HCC) remains high in numerous countries, including Thailand. There are numerous different lines of HCC treatment; however, various side effects and the resistance of cancer cells during treatment remain issues. At present, traditionally used herb plants have been widely used as alternatives to cancer therapy. Derris scandens is a Thai traditional herb which is commonly found in Thailand and widely used as a traditional me...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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