NICE are recruiting experts to revise their Fertility guideline

NICE are currently seeking to recruit topic experts for the update of the Fertility (assessment and treatment for people with fertility problems) guideline. The update will look at the effectiveness of intrauterine insemination (IUI), compared with expectant management, in people with unexplained infertility, mild endometriosis or ‘mild’ male factor infertility. They are looking for the following people: 1 x Consultant Level Clinical Scientist (Andrologist/Embryologist) 1 x GP 1 x Fertility Nurse 1 x Lay Member 4 x NHS Fertility Consultants Adverts for both the professional and lay members can be found on the NICE website at the following links: Healthcare Professional Members Lay Members Both adverts will close 5pm on Monday 7th September 2015. Key dates for meetings that must be attended are included in the advert – please take these into consideration when applying
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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ConclusionModerate-to-severe endometriosis was more common in women with East or South East Asian ethnicity in our tertiary referral center. This could be explained by East/South East Asians with minimal-mild disease being less likely to seek care, or genetic/environmental differences that increase the risk of more severe disease amongst East/South East Asians.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: July 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 1Author(s): Xianghui Zhang, Dong Liu, Wei Huang, Qiushi Wang, Xue Feng, Jing TanAbstractThe effect of endometriosis on fecundity is unclear. Although surgery plays a vital role in the treatment of related infertility, pregnancy outcomes after laparoscopy are poorly correlated with the currently used staging system. To address this, the Endometriosis Fertility Index (EFI) was developed. This retrospective study was designed to assess the predictive value of the EFI for patients with endometriosis-associated infertility. A total of 1325 pati...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
This study was performed on 168 infertile women referred to Ahvaz infertility center who were divided into two groups of infertile patients with cervical stenosis (n = 84) and the control group of infertile patients without cervical stenosis (n = 84). Demographic and clinical data of all individuals including age, body mass index (BMI), the duration of infertility, causes of infertility, history of medicine and surgical treatment, endometriosis, type of ovarian cyst, the presence of cervical myomas, polyps, and uterine septum (diagnosed by sonohysterography) were determined. Correlation between internal cervical os...
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
AbstractPurpose of ReviewAir pollution is widely known to affect human cardiopulmonary health, but only recently has research begun to focus on understanding the association between ambient air pollution and reproductive health and gynecologic disease incidence. In this article, we conducted a systematic literature review to examine studies conducted to evaluate the association between air pollution and the heterogeneous gynecologic diseases of infertility, menstrual irregularity, uterine fibroids, and endometriosis. In this review, the authors discuss exposure assessment considerations, outcome definitions, statistical an...
Source: Current Epidemiology Reports - Category: Epidemiology Source Type: research
Publication date: August 2018Source: Gynecologic Oncology Reports, Volume 25Author(s): Lisa N. Abaid, John S. Cupp, Miles Chang, Steven R. Beanes, Bram H. GoldsteinAbstractEndometriosis is a condition wherein an ectopic layer of endometrial tissue arises in an extra-uterine location, often effecting significant pelvic pain and infertility. While very uncommon, there have been reported cases of endometriosis undergoing malignant transformation, frequently involving the ovaries and seldom in extra-gonadal regions. We recount a case depicting a 63 year-old woman who presented with an apparent inguinal hernia in 2017; she wa...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
Publication date: Available online 15 February 2018Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Federico Prefumo, A. Cristina RossiAbstractEndometriosis and infertility are linked in a complex relationship, and a number of different pathogenetic mechanisms may associate the two. Endometriosis is diagnosed in 6–8% of women undergoing ART. Women with endometriosis appear to have similar ART outcomes compared to controls in terms of live birth rates, despite a lower oocyte quality. Laparoscopy should not be routinely performed before ART with the only aim to diagnose mild or moderat...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Publication date: Available online 14 February 2018Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Bansari G. Patel, Emily E. Lenk, Dan I. Lebovic, Yimin Shu, Jie Yu, Robert N. TaylorAbstractDespite an estimated prevalence of 11% in women and plausible historical descriptions dating back to the 17th century, the etiology of endometriosis remains poorly understood. Classical theories of the histological origins of endometriosis are reviewed below. Clinical presentations are variable, and signs and symptoms do not correlate well with the extent of disease. In this summary, we have attempted...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Publication date: Available online 18 June 2018Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Carla Tomassetti, Thomas D'HoogheAbstractWhen evaluating the correlation between endometriosis and infertility with application of the evidence-based guidelines to establish causality in medicine, it becomes apparent that endometriosis causes infertility. This is supported by a strong and consistent association between the two in various settings (prevalence, natural conception, intrauterine insemination (IUI), and assisted reproductive technologies (ARTs)), evidence for a temporal relation, arg...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Publication date: June 2018Source: Best Practice &Research Clinical Endocrinology &Metabolism, Volume 32, Issue 3Author(s): Ioannis Simitsidellis, Douglas A. Gibson, Philippa T.K. SaundersEndometriosis is a chronic incurable disorder that affects 1 in 10 women of reproductive age: associated symptoms include chronic pain and infertility. The aetiology of endometriosis remains poorly understood but patients, clinicians and researchers are all in agreement that new non-surgical therapies are urgently needed to reduce the severity of symptoms. Preclinical testing of drugs requires the development and validation of mod...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Purpose of review Surgery has traditionally been the primary treatment option for endometriosis-related infertility of any phenotype. However, advances and refinements of assisted reproductive technologies (ART) permit a more conservative approach in many scenarios. This review summarizes the latest findings in the field of reproductive medicine, which have supported a paradigm shift towards more conservative management of ovarian endometrioma. Recent findings The presence of ovarian endometrioma per se is likely to impair ovarian reserve and alter ovarian functional anatomy. Conventional laparoscopic surgery is assoc...
Source: Current Opinion in Obstetrics and Gynecology - Category: OBGYN Tags: REPRODUCTIVE ENDOCRINOLOGY: Edited by David L. Olive Source Type: research
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