Involvement of Rho-associated protein kinase (ROCK) and bone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER) in high glucose-increased alkaline phosphatase expression and activity in human coronary artery smooth muscle cells
Conclusions:
There are at least two independent pathways in high glucose-induced ALP activation in HCASMCs: the Rho–ROCK signaling pathway and the BMPER-dependent pathway.
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Yuya TeraoSeimi Satomi-KobayashiKen-ichi HirataYoshiyuki Rikitake Source Type: research
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