Does red meat affect male fertility?

ConclusionThis study of a cohort of men attending a fertility clinic for help to conceive found fertilisation rates in the laboratory during IVF were less successful if men reported a diet high in processed meat, and more successful if they ate more chicken. Importantly, the effect of overall meat intake was not related to fertility success, which is the chance of becoming pregnant after the treatment cycles, or having a live birth. It was also not clear whether the variation in fertility rate influenced how many cycles of IVF were needed, or how long the couple needed medical assistance, before they became pregnant or had a child. If more IVF cycles were needed, this would be more expensive, especially if people are paying for private fertility treatment.So what does this mixed bag of results tell us? It does not tell us processed meat causes lower fertility or chicken boosts it. That could be true, but there could be lots of reasons why the individual couples at the fertility clinic had difficulty conceiving – not all related to male fertility.Also, the amount of processed meat men eat could be a marker of how generally healthy their diet is, or how healthy they are in general, both of which may influence sperm development and fertility. The researchers did attempt to account for this in their analysis, but this might not completely eliminate the effects. Other relevant factors, such as smoking, have not been taken into account.The researchers say they previously foun...
Source: NHS News Feed - Category: Consumer Health News Tags: Food/diet Pregnancy/child Source Type: news

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Antonella Stoppacciaro, Serena Di Vito, Patrizia Filetici
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
In this study, a PEG-modified liposome was developed for efficiently encapsulating CBZ, thus enhancing its specific tumor inhibition effect and reducing the systemic toxicity. It was found that the loading efficiency of CBZ into the liposome could be improved with the increase of lipophilic materials, as it could be over 80% under the weight ratio of 20:1 (total lipid: CBZ). The diameter of CBZ loaded liposome (CBZ@Lipo) was ∼100 nm. And the liposome suspending in aqueous medium was stable at 4 °C for at least one month, according to the change of its size distribution. The killing ability of CBZ@Lipo to cancer cel...
Source: Asian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 19 November 2018Source: Journal of Herbal MedicineAuthor(s): Andrew Croaker, Graham J. King, John H. Pyne, Shailendra Anoopkumar-Dukie, Lei LiuAbstractBlack salve, used as an alternative skin cancer therapy, contains both herbal and chemical constituents, including extracts of the rhizomes of Sanguinaria canadensis and zinc chloride. Black salves may be ordered online and have been associated with cases of extensive tissue necrosis and treatment failures that have resulted in patient fatalities. Despite these adverse outcomes and continued use by patients, black salve products have not be...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Conclusion: In the most compromised lung cancer patients, VATS sublobar resection might be the best option.
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Thoracic Source Type: research
Conclusions: Our study suggests that the evaluation of lymph nodes via groin dissections in groin sarcomas in the Asian population should be based primarily on clinical and radiologic evidence. Regional lymph node dissection seems to confer OS benefit in patients with these high-risk tumors and can improve local control of disease.
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Soft Tissue Source Type: research
Conclusions: Cure with a microscopically positive margin was suboptimal (71%) despite patients having classic-histology papillary and follicular carcinoma, favorable stage, and moderate-dose I-131 therapy.
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Endocrine Source Type: research
Conclusions: These results affirm that patients with OMCC have extended OS periods and that stereotactic body radiotherapy offers strong local control in these settings. We show that even in the oligometastatic setting those with right-sided primary tumors have worse outcomes relative to those with left-sided or rectal primary tumors. This suggests more aggressive treatment may be needed for those with oligometastatic right-sided colorectal cancer.
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Gastrointestinal Source Type: research
Conclusions: About 25% of patients with PC treated without adjuvant RT develop LRRO as initial failure. The only independent predictor of LRRO was positive margin, while elevated postoperative CA 19-9 and pLN+ were associated with predicting MR and overall survival. These data may help determine which patients benefit from intensification of local therapy with radiation.
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Gastrointestinal Source Type: research
This study investigated the addition of celecoxib, a selective COX-2 inhibitor, to the irinotecan, 5-fluorouracil, and leucovorin (IFL) regimen for patients with previously untreated metastatic CRC. Patients and Methods: Forty-seven patients enrolled in this single-arm phase II study received celecoxib at 400 mg orally twice daily in combination with weekly irinotecan (125 mg/m2), 5-fluorouracil (500 mg/m2), and leucovorin (20 mg/m2) for 4 weeks every 6 weeks. The primary endpoint was response rate (RR) as measured by Response Evaluation Criteria in Solid Tumors. The protocol was amended midw...
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Gastrointestinal Source Type: research
Purpose/Objective(s): To determine if routinely replanning patients treated for oropharyngeal cancer that is p16-positive and clinical neck stage N2b (AJCC 7th edition) is likely to result in dose changes that will improve patient outcomes to a meaningful degree. Methods: In 10 consecutive patients treated with primary radiotherapy (RT) and concurrent weekly chemotherapy for p16-positive N2b oropharyngeal carcinoma, we prospectively evaluated dose changes from replanning for the final 4 or 2 weeks of RT of a 7-week RT program. Results: Replanning for the final 4 or 2 weeks improved planning target volume coverage b...
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Head and Neck Source Type: research
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