The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma

Conclusions
ERK5 regulates the biology of HCC cells and modulates tumour development and growth in vivo. This pathway should be investigated as a possible therapeutic target in HCC.

Source: Gut - August 7, 2015 Category: Gastroenterology Authors: Rovida, E., Di Maira, G., Tusa, I., Cannito, S., Paternostro, C., Navari, N., Vivoli, E., Deng, X., Gray, N. S., Esparis-Ogando, A., David, E., Pandiella, A., Dello Sbarba, P., Parola, M., Marra, F. Tags: Hepatic cancer Hepatology Source Type: research