Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study
Conclusions
The single-nucleotide polymorphisms rs10273639 at the PRSS1–PRSS2 locus and rs7057398 and rs12688220 at the CLDN2–MORC4 locus are associated with CP and strongly associate with ACP, but only rs7057398 with NACP in female patients.
Source: Gut - Category: Gastroenterology Authors: Derikx, M. H., Kovacs, P., Scholz, M., Masson, E., Chen, J.-M., Ruffert, C., Lichtner, P., te Morsche, R. H. M., Cavestro, G. M., PanEuropean Working group on Alcoholic Chronic Pancreatitis members and collaborators, Ferec, C., Drenth, J. P. H., Witt, H., Tags: Pancreas and biliary tract, Pancreatitis Source Type: research
More News: Alcoholism | Cirrhosis | Gastroenterology | Genetics | Pancreas | Pancreatitis | Study | Women