Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study

Conclusions The single-nucleotide polymorphisms rs10273639 at the PRSS1–PRSS2 locus and rs7057398 and rs12688220 at the CLDN2–MORC4 locus are associated with CP and strongly associate with ACP, but only rs7057398 with NACP in female patients.
Source: Gut - Category: Gastroenterology Authors: Tags: Pancreas and biliary tract, Pancreatitis Source Type: research

Related Links:

Condition:   Alcoholic Cirrhosis Intervention:   Other: Endoscopic ultrasound for detection of Chronic pancreatitis Sponsor:   Asian Institute of Gastroenterology, India Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Most people know about the damaging effects that binge drinking can bring to someone’s life. Loss of enjoyment of life, losing family relationships, financial and career struggles, homelessness, and legal consequences are just the tip of the iceberg. However, it can be more difficult to realize the long-term effect of binge drinking on the body, because you cannot always see it. Frequent binge drinking poses many dangerous health risks, and many of them can lead to death. Facts on Long-Term Effect of Binge Drinking on the Body For men, binge drinking is defined as consuming five or more drinks within about two hour...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism alcohol abuse alcohol dependence alcohol treatment alcohol treatment center binge binge drinking Source Type: blogs
CONCLUSIONS: The results of this analysis provide valuable insights for national and regional health policymakers in the process of preparing high-quality health regional plans, as well as retrospectively assessing the success of existing health policies and interventions in this area. Facts presented in the study justify the need for specialised health care, which is part of the process of building an Integrated Health Care Centre in Slovakia. PMID: 31901192 [PubMed - in process]
Source: Central European Journal of Public Health - Category: International Medicine & Public Health Tags: Cent Eur J Public Health Source Type: research
ConclusionDespite relatively stable trends in AH-related readmission, the total LOS and cost has been rising. A target-directed approach with a focus on high-risk subpopulations may help understand the unique challenges associated with the rising cost of AH-related readmissions.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Abstract Euglycemic DKA (eu-DKA) is a life-threatening emergency. It may occur in patients with both type 1 and type 2 DM, and characterized by milder degrees of hyperglycemia with blood glucose level 
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Eur J Intern Med Source Type: research
AbstractAlcohol and high-fat diet are two major risk factors responsible for metabolic diseases, which are manifested as steatohepatitis and liver cancer in the liver, and chronic pancreatitis and pancreatic adenocarcinoma (PDAC) in the pancreas. These metabolic diseases are becoming increasingly prevalent around the globe, and more importantly, their two major etiologies commonly coexist to precipitate the disease processes. To highlight the importance of these metabolic diseases, Japanese Society of Gastroenterology (JSGE) and National Institute on Alcoholism and Alcohol Abuse of National Institute of Health cosponsored ...
Source: Journal of Gastroenterology - Category: Gastroenterology Source Type: research
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Commentary Source Type: research
CONCLUSION: There may be opportunities to reach some of the patients who later develop alcoholic liver cirrhosis or pancreatitis with preventive interventions in the hospital setting. PMID: 29359016 [PubMed]
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
Intraoral lesion · history of cirrhosis and smoking · Dx? J Fam Pract. 2017 Oct;66(10):626-628 Authors: Ogbureke EI, Conn RE, Garcia DE, Johnson CD Abstract A 56-year-old white man presented at our dental clinic for routine care. The intraoral examination revealed an asymptomatic red lesion with white vesicle-like areas on the right side of the soft palate. The extraoral examination was normal, and regional lymph nodes were nonpalpable. The patient's medical history included liver cirrhosis and pancreatitis. He also had a 30-year history of alcohol misuse (1-5 drinks per day) and a 30-pa...
Source: The Journal of Family Practice - Category: Practice Management Authors: Tags: J Fam Pract Source Type: research
A 47-year-old man with alcohol-related cirrhosis and chronic pancreatitis presented with hematemesis. Upper endoscopy and colonoscopy demonstrated blood in the proximal small bowel, without active bleeding. The patient was hospitalized for 29 days for obscure gastrointestinal hemorrhage with intermittent episodes of hematemesis and hematochezia, for which 8 upper endoscopies, 3 colonoscopies, and 5 tagged red blood cell scans were performed. An image from final endoscopy performed in the intensive care unit for massive hematemesis demonstrated active bleeding emanating from the ampulla of Vater (Fig  1).
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Images in IR Source Type: research
More News: Alcoholism | Cirrhosis | Gastroenterology | Genetics | Pancreas | Pancreatitis | Study | Women