Outcomes after Chemotherapy Followed by Radiation for Stage IIB Hodgkin Lymphoma with Bulky Disease

Conclusion Stage IIB bulky HL patients had excellent outcomes after combined-modality therapy. Treatment strategies have changed substantially over time, with concomitant improvements in disease outcomes and long-term toxicities. Teaser Treatment for stage II bulky Hodgkin lymphoma with B symptoms is controversial, with patients treated using either early-stage or advanced disease treatment paradigms, varying greatly by institution. We reviewed patients with stage IIB bulky disease at our institution treated primarily with combined-modality therapy and found that these patients had generally excellent outcomes when treated with ABVD followed by consolidative radiation and superior outcomes when compared to advanced-stage patients. Furthermore, outcomes have improved over time, likely secondary to the reduction of treatment-associated toxicities.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research