Evaluating Social Media Networks in Medicines Safety Surveillance: Two Case Studies

Conclusions Publicly available data from the considered social media networks were sparse and largely untrackable for the purpose of providing early clues of safety concerns regarding the prespecified case studies. Further research investigating other case studies and exploring other social media platforms are necessary to further characterise the usefulness of social media for safety surveillance.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research

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Authors: Ashrafi MR, Amanat M, Garshasbi M, Kameli R, Nilipour Y, Heidari M, Rezaei Z, Tavasoli AR Abstract Introduction: Leukodystrophies constitute heterogenous group of rare heritable disorders primarily affecting the white matter of central nervous system. These conditions are often under-appreciated among physicians. The first clinical manifestations of leukodystrophies are often nonspecific and can occur in different ages from neonatal to late adulthood periods. The diagnosis is, therefore, challenging in most cases.Area covered: Herein, the authors discuss different aspects of leukodystrophies. The authors used...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Annelies Wilder-Smith, Stefan Flasche, Peter G Smith
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionThe present study reports a variant subgroup GII-a PEDV HM2017 strain in China and characterize its pathogenicity. PEDV strain HM2017 of subgroup GII-a presents a promising vaccine candidate for the control of PED outbreaks in China.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
In this study H. pylori CagL gene was cloned in pAMJ2008 vector and transferred to Lactococcus lactis MG1363 as the host for CagL antigen production. This recombinant bacterium was orally subjected to mice, and the immune response to CagL was evaluated by ELISA. Intracellular expression of CagL protein was confirmed by Western blot analysis. Mucosal immunization of mice with the recombinant L. lactis significantly stimulated CagL-Specific antibodies: IgA, IgG, cytokine IL-17 and IN-γ. Moreover, the specific anti-CagL IgA response was detected in the feces of immunized mice. These results indicate that CagL of H. pylo...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsThis study provides initial perspectives on measles preparedness among Idaho CAHs, despite limited generalizability. Future studies should explore whether self-reported preparedness measures reflect the ability of the CAHs to control measles spread when cases present for care.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
A financially troubled Seattle research institute cut back programs, leaving researchers to find new homes for work on infectious diseases like tuberculosis and leprosy.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Infectious Disease Research Institute Vaccination and Immunization Tuberculosis Philanthropy Nonprofit Organizations Drugs (Pharmaceuticals) Leprosy (Hansen ' s Disease) Leishmaniasis Layoffs and Job Reductions Seattle (Wash) your- Source Type: news
Publication date: Available online 24 September 2019Source: Canadian Journal of DiabetesAuthor(s): Vincent C. WooAbstractAdults with type 2 diabetes mellitus can benefit from pharmacotherapies that lower their risk for cardiovascular disease. This review describes the salient findings from sodium-glucose cotransporter-2 (SGLT2) inhibitor cardiovascular outcome trials that serendipitously revealed the cardiorenal benefits of SGLT2 inhibitors in adults with type 2 diabetes mellitus who either have established cardiovascular disease or multiple cardiovascular risk factors. It also summarizes the findings from other phase 3 cl...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
(CNN/CBS) — At least 1,300 people have died from the flu so far this season, according to a preliminary estimate released Friday by the US Centers for Disease Control and Prevention. There have been at least 2.6 million flu illnesses and 23,000 flu-related hospitalizations, according to the analysis. So far this season, the CDC has received reports of 10 children who have died from the flu, four more than the week before. Experts have warned that flu is hitting the United States early this year, and there are concerns that this early season could mean a particularly severe season overall. Flu spread significantly in ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Flu Source Type: news
In this study, 37.0% (n=452) of the population were admitted directly to Hospital de Braga and 63.0% (n=770) were transferred from other hospitals. Although timings (in min) until reperfusion were longer in interhospital transfer patients (symptom onset-first medical contact (median 76.5, IQR 40.3–150 vs. 91.0, IQR 50–180, p=0.002), first medical contact-reperfusion (median 87.5, IQR 69.0–114 vs. 145, IQR 115–199, p
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
Publication date: Available online 12 December 2019Source: Revista Española de Cardiología (English Edition)Author(s): Emad Abu-Assi, José L. Bernal, Sergio Raposeiras-Roubin, Francisco J. Elola, Cristina Fernández Pérez, Andrés Íñiguez-RomoAbstractIntroduction and objectivesThere are few data on the safety of length of stay in uncomplicated ST-segment elevation myocardial infarction. We studied trends in hospital stay and the safety of short (≤ 3 days) vs long hospital stay in Spain.MethodsUsing data from the Minimum Basic Data Set, we identified patients with unc...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
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