This Device Can Zap Your Brain Into A State Of Zen. Is That A Good Thing?

What if you could zap your brain into a state of calm or energy with only the push of a button? It may sound like the stuff of sci-fi, but it's now the promise of a new class of tech wearables created by teams of Silicon Valley entrepreneurs and neuroscientists. Several devices have come onto the market claiming to use brain stimulation to alter an individual's mental state. One of the latest is Thync Vibes ($299), a stick-on device that delivers low-grade electrical pulses ("vibes") into the scalp to cause a change in automatic nervous system activity.  How does it actually work? Those who are brave enough to try it will stick a small triangular device onto the side of the forehead and attach another small strip to the back of the neck or behind the ear. Using the Thync iPhone app, you adjust the intensity and duration of the session, which can range from 5 to 20 minutes. During that time, pulses of electricity will activate either your parasympathetic nervous system (the "rest and digest" system, which slows the heart rate) or your sympathetic nervous system (responsible for the "fight or flight" response), depending on whether you choose the "calm" or "energy" setting.  Thync, which is led by CEO Isy Goldwasser and neuroscientist/chief scientific officer Jamie Tyler, aims to "bring neuroscience to everyday people." So far, the company has received more than $13 million from inves...
Source: Science - The Huffington Post - Category: Science Source Type: news

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This study investigated whether the LRRK2 G2385R variant was associated with a unique clinical phenotype of PD in the Asian population, using a meta-analysis. The PubMed, Web of Science, EMBASE, CNKI, and WANFANG databases were searched until September 2017. The strict selection criteria and exclusion criteria were determined, and mean differences (MD) or odds ratios (OR) with 95% confidence intervals (CI) were used to assess the strength of associations. Statistical analyses and graphics were performed using Review Manager 5.3. Sixteen related case-control studies were included in the meta-analysis. The LRRK2 G2385R carri...
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
Publication date: September–October 2018Source: Brain Stimulation, Volume 11, Issue 5Author(s): Samer Mohsen, Saeid Mahmoudian, Saeed Talebian, Akram Pourbakht
Source: Brain Stimulation - Category: Neurology Source Type: research
This study included 56 TRD patients [67.8%: women; mean age (SD): 45.5 (10.6) years], who were randomly assigned to one of four groups [A: right prefrontal cTBS; B: left prefrontal iTBS; C: combined right prefrontal cTBS and left prefrontal iTBS; and D: sham-TBS]. We measured standard uptake values (SUV) of cerebral glucose metabolism, at rest, both before and after ten daily treatment sessions.ResultsGroup B and Group C had more responders than Group A and Group D (χ2 = 9.161, p = 0.027). In Group A, the SUV was significantly increased in the ACC and medial PFC (mPFC) after treatment, while the SUV was decreas...
Source: Brain Stimulation - Category: Neurology Source Type: research
Authors: Bhat A, Cerimele JM, Byatt N Abstract Up to 20% of women who screen positive for depression in the perinatal period in primary care and obstetric settings may have bipolar disorder, but little is known about best practices for this population. This column describes clinical programs that support identification and management of depression and bipolar disorder among women in non-mental health settings. The programs use diverse management strategies, including referral to specialty mental health, collaborative care, and consultation and care coordination. Most mental health programs based in primary care and...
Source: Psychiatric Services - Category: Psychiatry Tags: Psychiatr Serv Source Type: research
CONCLUSION: In patients with DPD, the structural connectivity between brain regions crucial for multimodal integration and emotion regulation may be altered. Aberrations in fibre tract communication seem to be not solely a secondary effect of local grey matter volume loss, but may present a primary pathophysiology in patients with DPD. PMID: 30125247 [PubMed - in process]
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research
Authors: Kim SJ, Roh D, Jung HH, Chang WS, Kim CH, Chang JW Abstract BACKGROUND: Recently, a new thermal lesioning approach using magnetic resonance-guided focused ultrasound (MRgFUS) was introduced for the treatment of neurologic disorders. However, only 2 studies have used this approach for treatment-refractory obsessive-compulsive disorder (OCD), and follow-up was short-term. We investigated the efficacy and safety of bilateral thermal lesioning of the anterior limb of the internal capsule using MRgFUS in patients with treatment-refractory OCD and followed them for 2 years. METHODS: Eleven patients with trea...
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research
CONCLUSIONS: Our findings stress the importance of including both maternal and paternal psychopathology in future studies and interventions focusing on early childhood aggressive behaviour. PMID: 30125784 [PubMed - as supplied by publisher]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Authors: Williams SM, Frey LM, Stage DL, Cerel J Abstract Gender and sexual minorities (GSM) are at a higher risk for victimization, discrimination, and emotional distress. GSM also face unique stressors that contribute to negative mental health outcomes, such as family and interpersonal rejection, ostracism and isolation, and internalized gender and sexual stigma. Suicide attempt survivors often experience similar stigma and isolation after an attempt. However, little is known about the specific experiences of GSM individuals who attempt suicide. Transcripts of interviews with 25 GSM attempt survivors conducted as...
Source: The American Journal of Orthopsychiatry - Category: Psychiatry Tags: Am J Orthopsychiatry Source Type: research
Conclusions: BNG-1 mediated changes in PDE3B expression along with reduction in oxidative stress and inflammation. BNG-1 may ameliorate insulin resistance and hepatic steatosis in the NAFLD mouse model. PMID: 30123057 [PubMed - in process]
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Conclusions: Serum antigen-specific IgE, as well as total IgE, is significantly associated with CVDs independently of a long list of established cardiovascular risk factors, which is more informative than total IgE per se. PMID: 30123046 [PubMed - in process]
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
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