American Gastroenterological Association Institute Guideline on the Diagnosis and Management of Lynch Syndrome

This document presents the official recommendations of the American Gastroenterological Association (AGA) Institute on the diagnosis and management of Lynch syndrome. Lynch syndrome (previously referred to as hereditary nonpolyposis colorectal cancer syndrome) is the most common heritable colorectal cancer syndrome, accounting for 2% to 3% of colorectal cancers, and has an estimated prevalence in the general population of 1 in 440. Patients with Lynch syndrome have an estimated lifetime cumulative incidence of colorectal cancer up to 80% and endometrial cancer up to 60% and also have increased risks of other cancers, including stomach, small intestine, pancreas, biliary tract, ovary, urinary tract, and brain.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: AGA Section Source Type: research