Sector Resection With or Without Postoperative Radiotherapy for Stage I Breast Cancer: 20-Year Results of a Randomized Trial.

CONCLUSION: Radiotherapy protects against recurrences during the first 5 years of follow-up, indicating that XRT mainly eradicates undetected cancer foci present at primary treatment. The similar rate of recurrences beyond 5 years in the two groups indicates that late recurrences are new tumors. There are subgroups with clinically relevant differences in risk.
PMID: 24493730 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - February 3, 2014 Category: Cancer & Oncology Authors: Wickberg A, Holmberg L, Adami HO, Magnuson A, Villman K, Liljegren G Tags: J Clin Oncol Source Type: research