Pre-Transplant Weight Loss and Survival after Kidney Transplantation

We examined post-transplant survival among obese kidney candidates who were temporarily designated waitlist inactive (status 7) due to their weight. Methods: Using OPTN/United Network for Organ Sharing data, patient and graft survival of adult status 7 recipients with a registration body mass index (BMI) ≥30 kg/m2 (n = 328) were compared to all others (controls; n = 74,066). Status 7 recipients were then matched to controls to assess whether pre-transplant weight loss was associated with a survival benefit. Results: Median BMI at registration (38 vs. 27 kg/m2, p
Source: American Journal of Nephrology - Category: Neurology Source Type: research

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Transplant International,Volume 0, Issue ja, -Not available-.
Source: Transplant International - Category: Transplant Surgery Authors: Source Type: research
Clinical Transplantation,Volume 0, Issue ja, -Not available-.
Source: Clinical Transplantation - Category: Transplant Surgery Authors: Source Type: research
Adverse effects of chronic nicotine exposure on the kidney: Potential human health implications of experimental findings
. Int J Clin Pharmacol Ther. 2018 Aug 27;: Authors: Arany I, Taylor M, Fülöp T, Dixit M Abstract With the increasing popularity of E-cigarettes, chronic exposure to nicotine (NIC) is emerging as a novel risk factor for the kidney. NIC increases oxidative stress in the kidneys, which impairs the viability and function of renal tubular and endothelial cells, alters renal hemodynamics, and compromises overall kidney function. Moreover, long-term NIC exposure increases the ri...
Source: International Journal of Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
AbstractPurposeLife span and sense of well-being continue to improve post-transplantation in patients with end-stage kidney disease, despite referral of an older and more medically complex population for transplantation. In this issue of the journal, we review existing evidence about risk assessment in kidney transplant candidates from the perspective of the anesthesiologist. The authors explore cardiovascular assessment and risk in the context of intraoperative events that can influence short- and long-term outcomes.Recent FindingsThe number of patients referred for kidney transplantation continues to increase and has far...
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research
Chronic kidney disease (CKD) currently affects approximately 15% of the US population or 30 million US adults,1 but incidence is projected to increase over the next 2 decades due to the ongoing obesity epidemic and the aging of the US population.2 Almost half of all US adults aged 65 years and older are predicted to develop CKD during their lifetime.2 The economic impact of CKD is substantial. Despite the fact that end-stage renal disease (ESRD), the most severe stage of CKD requiring kidney transplant or dialysis, is experienced only 650,000 US persons, the Medicare costs alone exceed $33 billion annually.
Source: Journal of the American Dietetic Association - Category: Nutrition Authors: Tags: From the Academy Source Type: research
AbstractPurpose of ReviewTo educate nephrologists and primary-care physicians about the incidence, pathophysiology, and survival benefits of the obesity paradox in end-stage renal disease (ESRD). This review also discusses the future of kidney transplant and peritoneal dialysis in obese dialysis patients.Recent FindingsObesity paradox in ESRD was first reported three decades ago, and since then, there have been several epidemiological studies that confirmed the phenomenon. Regardless of the anthropometric indices used to define obesity in ESRD patients, these markers serve to predict the dialysis patient ’s survival....
Source: Current Hypertension Reports - Category: Primary Care Source Type: research
We presently forget 98% of everything we experience. That will go away in favor of perfect, controllable, configurable memory. Skills and knowledge will become commodities that can be purchased and installed. We will be able to feel exactly as we wish to feel at any given time. How we perceive the world will be mutable and subject to choice. How we think, the very fundamental basis of the mind, will also be mutable and subject to choice. We will merge with our machines, as Kurzweil puts it. The boundary between mind and computing device, between the individual and his or her tools, will blur. Over the course of the ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Purpose of review Robotic pancreas transplantation is a novel procedure that aims to reduce surgical invasiveness, and thereby limit complications related to the surgical access. Given that few centers are providing robotic transplantation, this review serves as a state of the science article to outline early experiences and highlight areas for future research. Recent findings Pancreas transplantation results in relatively high rates of wound and other surgical complications that are known to deleteriously impact outcomes. The minimally invasive, robotic-assisted approach decreases wound complications. Because of the ...
Source: Current Opinion in Organ Transplantation - Category: Surgery Tags: PANCREAS TRANSPLANTATION: Edited by Peter Abrams Source Type: research
Publication date: June 2018Source: American Journal of Kidney Diseases, Volume 71, Issue 6Author(s): Yoshitsugu Obi, Elani Streja, Rajnish Mehrotra, Matthew B. Rivara, Connie M. Rhee, Melissa Soohoo, Daniel L. Gillen, Wei-Ling Lau, Csaba P. Kovesdy, Kamyar Kalantar-ZadehBackgroundThe prevalence of severe obesity, often considered a contraindication to peritoneal dialysis (PD), has increased over time. However, mortality has decreased more rapidly in the PD population than the hemodialysis (HD) population in the United States. The association between obesity and clinical outcomes among patients with end-stage kidney disease...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
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