Can low-frequency repetitive transcranial magnetic stimulation precipitate a late-onset seizure in a stroke patient?

Repetitive transcranial magnetic stimulation (rTMS) therapy is being increasingly used in various neuropsychiatric conditions. Literature suggests accidental seizure induction as the most serious adverse effect of rTMS. Several incidents of seizure induction were reported prior to the advent of safety guidelines for TMS parameters (Wassermann, 1998; Rossi et al., 2009). But after the publications of updated safety guidelines (Rossi et al., 2009), only two cases of seizure induction have been reported where rTMS was used within the safety framework.

Source: Clinical Neurophysiology - July 23, 2015 Category: Neuroscience Authors: Nand Kumar, MV Padma Srivastava, Rohit Verma, Hina Sharma, Tamonud Modak Tags: Letter to the Editor Source Type: research