Gambia: Prevent Malaria

[Daily Observer] The rainy season began. During this period, the country records the highest incident of malaria. The downpour often renders some community roads unmotorable, stagnant waters here and there and above all unwanted weeds show their ugly faces everywhere.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news

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We examined factors related to the uptake of two malaria prevention measures, insecticide-treated bed-nets and prophylactic sulphadoxine-pyrimethamine (SP), among pregnant women in Nnewi, Nigeria. The survey had a quantitative and qualitative part. For each part, the subjects meeting our inclusion criteria were systematically identified in a population-based manner. For the qualitative part, focused group discussions, in-depth interviews with a wide variety of stakeholders (e.g., health workers, males whose wives are pregnant, and drug and net sellers), and key informants including doctors and nurses were held. All data co...
Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
[The Conversation Africa] The infectious disease burden in Africa is very high, particularly for tuberculosis (TB), malaria and HIV/AIDS. In 2018, nearly a quarter (24%) of TB cases in the world were in Africa. The region accounted for 93% of malaria cases. The continent also bears the brunt of the HIV epidemic: 20.6 million of the 37.9 million people living with HIV are in eastern and southern Africa.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
We present the case of a patient with a second-degree open dislocated ankle fracture and a complex wound situation as well as fever in the postoperative course. The man, originally from Nigeria, spent his annual holidays in a rural area of ​​the country, where he sustained a right-sided open dislocation fracture of his ankle in a car accident. After initial rudimentary care in Nigeria, the patient traveled back to Switzerland on his own, where he has been living for the past ten years. Back in Zurich he presented himself to our Department for Emergency Medicine. He was admitted to our Trauma Unit and received surgical ...
Source: Praxis - Category: General Medicine Authors: Tags: Praxis (Bern 1994) Source Type: research
J. L. Abbate et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Mass and continuous distribution channels have significantly increased access to insecticide-treated nets (ITNs) in Ghana since 2000. Despite these gains, a large gap remains between ITN access and use.
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
Development of effective malaria vaccines requires delivery platforms to enhance the immunogenicity and efficacy of the target antigens. This is particularly challenging for transmission-blocking malaria vaccines (TBVs), and specifically for those based on the Pfs25 antigen, that need to elicit very high antibody titers to stop the parasite development in the mosquito host and its transmission. Presenting antigens to the immune system on virus-like particles (VLPs) is an efficient way to improve the quantity and quality of the immune response generated. Here we introduce for the first time a new VLP vaccine platform, based...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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Source: Pediatric Hematology and Oncology - Category: Pediatrics Authors: Source Type: research
This study can help build a better spatially explicit predictive model for malaria in Kenya capturing the role and spatial distribution of environmental, social, behavioral, and other characteristics of the households.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Publication date: Available online 11 December 2019Source: Journal of Molecular StructureAuthor(s): Terence J. Noonan, Kelly Chibale, Susan A. Bourne, Mino R. CairaAbstractA crystal engineering approach combined with experimental screening methods was employed as a preformulation step for producing expectedly useful forms of a novel antimalarial drug lead (MMV652103). In previous experiments, this drug lead had shown promise both in vitro and in vivo against the human malaria parasite Plasmodium falciparum. Various new forms of MMV652103 were produced earlier, including co-crystals, a salt, polymorphs and a hydrated form a...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
In conclusion, the aqueous stem extract of B. alnoides possesses antimalarial properties. A single oral dose of 5000 mg/kg body weight had no significant toxic effects on the function and structure of the kidneys and liver. These results support its use in traditional medicine for the treatment of malaria. PMID: 31814839 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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