Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt

Conclusions This study demonstrates, for the first time, that SHIP2 is frequently downregulated in gastric cancer, and reduced SHIP2 expression promotes tumorigenesis and proliferation of gastric cancer via activation of the PI3K/Akt signaling.

http://link.springer.com/10.1007/s00535-015-1101-0

Source: Journal of Gastroenterology - July 23, 2015 Category: Gastroenterology Source Type: research