Drug Dosages Questioned in Diabetic Macular Edema TrialDrug Dosages Questioned in Diabetic Macular Edema Trial

Experts wonder whether increased doses might eliminate the advantages seen with aflibercept over bevacizumab and ranibizumab in a diabetic macular edema trial. Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Ophthalmology News Source Type: news

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K. K. Mali*, Sucheta S. Ligade and R. J. Dias
Source: Indian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research
Objectives: Hypertension occurs frequently among black populations around the world. In the United States (US) health system, interventions since the 1960s resulted in improvements in hypertension awareness, management and control among African Americans. This is in stark contrast to current health systems in African countries. To objectively assess the current situation in South Africa, we compared the cardiovascular health status of African Americans from 1960 to 1980 to black South Africans from recent years, as there is potential to implement best practices from the US. We also reviewed the recent cardiovascular heal...
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Background and method: The Australian Diabetes, Obesity, and Lifestyle Study is a national, population-based examination of ∼11 000 adults with a third follow-up phase at 12 years. The aim was to use ambulatory blood pressure monitoring (ABPM) in a subsample (n = 508) of the main Australian Diabetes third follow-up cohort to determine the proportion with established, masked or white-coat hypertension in city and regional centers and the effectiveness of diagnosis and treatment. Results: Mean age was 58.9 years, BMI was 27.6 kg/m2 with 53% women. The mean clinic BP was 127/73 mmHg and mean 24-h BP was 121...
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Conclusion: Total volume as well as duration of leisure time cross-country skiing are each continuously, inversely, and independently associated with future risk of hypertension in a white male population.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology Source Type: research
Conclusion: ANNs models including a PWV index could be used as promising approaches for predicting CHD risk without the need for invasive diagnostic methods and may help in the clinical decision.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research
Conclusion: One-third of the hypothesized association between body fat and LVMI was mediated by BP and glucose in this population-based cohort. Leptin was also an important mediator. Visceral adipose tissue was not more closely related to LVMI than subcutaneous abdominal fat.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Conclusions. Our findings suggest that outcomes and response to treatment with HLA DSA− MVI patients are similarly poor to those with DSA+ MVI patients, supporting a critical role for MVI in the diagnosis of AMR.
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research
In this study a unique non-enzymatic electrochemical glucose sensor was developed, utilising a gold honeycomb-like framework upon which sharp Co3O4 needles are anchored. This composite nanomaterial demonstrates excellent sensing performance in glucose concentrations ranging between 20 μM and 4 mM, exceeding the range required for non-invasive glucose sensing. In conjunction with this high sensitivity (2.014 mA mM−1·cm−2), the material possesses excellent selectivity towards glucose for commonly interfering physiological species such as uric acid and ascorbic acid. Glucose detection in syntheti...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
San Francisco-based digital therapeutics company Omada Health has raised $73 million as it looks to enlarge its arsenal for managing chronic diseases, the company said Wednesday. "From a broad standpoint, the way we address the most vexing health issues we’re up against — the way we can do good clinical work remotely — is not up to the level that it can be," said Omada Health CEO and co-founder Sean Duffy. Omada’s more than 130 coaches provide individualized supp ort guided by machine learning…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
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